Results 61 to 70 of about 13,871 (164)
International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
Topoisomerase I poisons-induced autophagy: Cytoprotective, Cytotoxic or Non-protective
Autophagy Reports, 2023 Topoisomerase I inhibitors represent a widely used class of antineoplastic agents that promote both single-stranded and double-stranded breaks in the DNA of tumor cells, leading to tumor cell death.
Ahmed M. Elshazly +3 more
doaj +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha +4 more
wiley +1 more source
Case Reports in Oncology, 2014 Introduction: Recurrent cervical cancer is associated with a poor prognosis. Most treatment responses are partial and of short duration. The development of new therapies is vital to improve treatment for recurrent disease.
Donato Callegaro-Filho +4 more
doaj +1 more source
The Plant Genome, Volume 19, Issue 3, September 2026.Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.Chest contrast‐enhanced computed tomography. A slightly enhanced solid intraluminal mass is observed in the left (green arrow) and right (yellow arrow) main pulmonary arteries. ABSTRACT We report a case of pulmonary artery intimal sarcoma successfully treated with surgical resection followed by weekly paclitaxel.
Fumitaka Endo +6 more
wiley +1 more source
Cancer, Volume 132, Issue 15, 1 August 2026.ABSTRACT Background Lung metastases in patients with metastatic rhabdomyosarcoma (RMS) have not been treated uniformly across Europe. This provides comparison of the impact of whole lung irradiation (WLI). Methods Lung‐metastatic patients included in the Cooperative Weichteilsarkom Studiengruppe‐IV 2002, European Pediatric Soft Tissue Sarcoma Study ...
Amadeus T. Heinz +14 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu +7 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 3, Page 719-728, 1 August 2026.What's New? The emerging role of immunotherapy in small‐cell lung cancer treatment has not been fully elucidated, particularly outside of clinical trials. This single‐center retrospective cohort study examined real‐world treatment patterns and overall survival in South Korea during the 2018–2023 period.
Sehhoon Park +11 more
wiley +1 more source
Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience
Pharmaceutics, 2020 A key limitation to glioma treatment involves the blood brain barrier (BBB). Convection enhanced delivery (CED) is a technique that uses a catheter placed directly into the brain parenchyma to infuse treatments using a pressure gradient.
Pavan S. Upadhyayula +4 more
doaj +1 more source