Results 71 to 80 of about 21,333 (293)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Research on the potential of the biopreparation VVH 86086 as a biological tool for the topping of inflorescences of tobacco grown for seed production

Растениевъдни науки, 2020
An important characteristic of tobacco seeds is their different quality caused by biological or physiological reasons. This different quality is due to the different conditions of the formation and maturation of seeds in seed capsules of each ...
Hristo Bozukov, Yovcho Kochev, Maria Kasheva   +2 more
doaj  

Top couplings and top partners

Journal of Physics: Conference Series, 2013
We review the model-independent description of the couplings of the top quark to the Higgs and gauge bosons in theories beyond the Standard Model. Then we examine these couplings in the case of arbitrary heavy vector-like quarks mixing with the third family.
Aguilar Saavedra, Juan Antonio, Pérez-Victoria, Manuel   +1 more
openaire   +3 more sources

Biomechanical changes of degenerated adjacent segment and intact lumbar spine after lumbosacral topping-off surgery: a three-dimensional finite element analysis

BMC Musculoskeletal Disorders, 2019
Background Previous studies have revealed positive effect of Topping-off technique on upper adjacent segment after fusion surgery, while for the cases with fusion surgery on L5-S1 segment, owning maximal range of motion, and preexisting degenerated upper
Liangliang Cao, Yumei Liu, W. Mei, Jianguang Xu, Shi Zhan   +4 more
semanticscholar   +1 more source

Early topping: an alternative to standard topping increases yield in cannabis production

, 2020
In commercial settings, cannabis is generally propagated through cuttings, a process referred in the industry as cloning. Some producers perform either topping or fimming to trigger the production of axillary shoots, which will enhance the number of ...
S. Gaudreau, T. Missihoun, H. Germain
semanticscholar   +1 more source

Topping-Off Technology versus Posterior Lumbar Interbody Fusion in the Treatment of Lumbar Disc Herniation: A Meta-Analysis

BioMed Research International, 2020
The treatment effects of topping-off technique were still controversial. This study compared all available data on postoperative clinical and radiographic outcomes of topping-off technique and posterior lumbar interbody fusion (PLIF). PubMed, EMBASE, and
Wei Wang, Xiangyao Sun, Tongtong Zhang, Siyuan Sun, C. Kong, Shibao Lu   +5 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Manejo do dossel vegetativo e seu efeito nos componentes de produção da videira Merlot Canopy management and its effect on the yield components of the Merlot grapevine

Revista Brasileira de Fruticultura, 2012
A poda verde é uma prática cultural utilizada para melhorar as condições do dossel vegetativo dos vinhedos, visando a favorecer a qualidade da uva e do vinho.
Alberto Miele, Francisco Mandelli
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source