Results 31 to 40 of about 11,616,493 (245)

Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies

Frontiers in Immunology, 2019
Background: Primary Immunodeficiencies (PIDs) are a heterogeneous group of genetic immune disorders. While some PIDs can manifest with more than one phenotype, signs, and symptoms of various PIDs overlap considerably.
Cristina Cifaldi, Immacolata Brigida, Federica Barzaghi, Federica Barzaghi, Federica Barzaghi, Matteo Zoccolillo, Matteo Zoccolillo, Valentina Ferradini, Davide Petricone, Maria Pia Cicalese, Maria Pia Cicalese, Maria Pia Cicalese, Dejan Lazarevic, Davide Cittaro, Maryam Omrani, Enrico Attardi, Francesca Conti, Alessia Scarselli, Maria Chiriaco, Silvia Di Cesare, Francesco Licciardi, Montin Davide, Francesca Ferrua, Francesca Ferrua, Francesca Ferrua, Clementina Canessa, Clementina Canessa, Claudio Pignata, Silvia Giliani, Simona Ferrari, Georgia Fousteri, Graziano Barera, Pietro Merli, Paolo Palma, Simone Cesaro, Marco Gattorno, Antonio Trizzino, Viviana Moschese, Viviana Moschese, Loredana Chini, Loredana Chini, Anna Villa, Anna Villa, Chiara Azzari, Chiara Azzari, Andrea Finocchi, Andrea Finocchi, Franco Locatelli, Paolo Rossi, Paolo Rossi, Federica Sangiuolo, Alessandro Aiuti, Alessandro Aiuti, Alessandro Aiuti, Caterina Cancrini, Caterina Cancrini, Gigliola Di Matteo, Gigliola Di Matteo   +57 more
doaj   +1 more source

Ion Torrent output

, 2017
Ion Torrent ...
Burke, Terence, J. W. Arntzen (3271848), Wielstra, Ben, Arntzen, J. W., Roger Butlin (128964), Ben Wielstra (132374), Terence Burke (5013401), Butlin, Roger   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Ion Torrent filtered A

, 2017
Filtered Ion Torrent data for Triturus cristatus part ...
Wielstra, Ben, ZieliŃski, Piotr, Babik, WiesŁaw   +2 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Ion Torrent unprocessed B

, 2017
Unprocessed Ion Torrent data for Triturus cristatus part ...
Wielstra, Ben, ZieliŃski, Piotr, Babik, WiesŁaw   +2 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Medición "in situ" de la permeabilidad al aire del hormigón: status quo Concrete air permeability "in situ "test status quo

Revista Ingeniería de Construcción, 2010
Los autores han estado involucrados en la creación y primeros ensayos y desarrollos del llamado "Método Torrent" para medir la permeabilidad al aire del hormigón.
Luis Ebensperger, Roberto Torrent
doaj  

Impact of DNA Sequencing and Analysis Methods on 16S rRNA Gene Bacterial Community Analysis of Dairy Products

mSphere, 2018
DNA sequencing and analysis methods were compared for 16S rRNA V4 PCR amplicon and genomic DNA (gDNA) mock communities encompassing nine bacterial species commonly found in milk and dairy products.
Zhengyao Xue, Mary E. Kable, Maria L. Marco   +2 more
doaj   +1 more source