Results 31 to 40 of about 8,444 (159)

Bradycardia and Other Arrhythmias in Patients With Hepatorenal Syndrome‐Acute Kidney Injury Following Terlipressin Treatment: A Pooled Analysis of Three North American Phase III Clinical Studies

Alimentary Pharmacology &Therapeutics, EarlyView.
In a pooled analysis, bradycardia was observed in 6% of terlipressin‐treated patients but rarely required a dose interruption or reduction. Arrhythmia serious adverse event incidences were low and similar in both treatment groups. Routine intensive cardiac monitoring for the detection of arrhythmias may not be necessary during terlipressin ...
Jasmohan S. Bajaj, Paul Kwo, Stephen Chris Pappas, Jacqueline G. O'Leary, Khurram Jamil, Sanaz Cardoza, Florence Wong   +6 more
wiley   +1 more source

Sodium glucose co‐transporter 2 inhibitors versus dipeptidyl peptidase‐4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population‐based cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang, Pauline Reynier, Antonios Douros, Oriana H. Y. Yu, Robert W. Platt, Kristian B. Filion   +5 more
wiley   +1 more source

A Rare Case of Thiamine Deficiency Leading to Dry Beriberi, Peripheral Neuropathy, and Torsades De Pointes [PDF]

, 2023
Trevor Phinney, Kathlyn Callenius, Madhurmeet Singh, Kristin Juhasz, Mirsha Stiven, Jeffrey R. Tseng   +5 more
openalex   +1 more source

The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated the age‐ and sex‐related differences in the apicobasal repolarization gradient (ABRG) and evaluated their possible role inventricular arrhythmia vulnerability. Electrocardiographic imaging (ECGI) was performed in healthy subjects during sinus rhythm, and the average recovery time (RT) and activation–recovery ...
Vladimír Sobota, Job Stoks, Kiran Haresh Kumar Patel, Roshni Shetty, Haibo Ni, Eleonora Grandi, Fu Siong Ng, Paul G. A. Volders, Matthijs J. M. Cluitmans, Jason D. Bayer   +9 more
wiley   +1 more source

Torsades de Pointes Triggered by Transient Low‐Rate Pacing Following Leadless Pacemaker Implantation

Journal of Arrhythmia, Volume 41, Issue 6, December 2025.
A case of torsades de pointes triggered by transient bradycardia during Micra AV2 setup highlights a proarrhythmic risk of automated initialization. Individualized programming may be necessary in high‐risk patients with QT prolongation.
Yumetsugu Munakata, Junji Morita, Yuhei Kasai, Takayuki Kitai, Yusuke Kondo   +4 more
wiley   +1 more source

Trends in drug–drug interaction prevalence and longitudinal associations with health outcomes in the older community‐dwelling population: Findings from The Irish LongituDinal study on Ageing

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3244-3256, November 2025.
Aims We estimate trends in severe drug–drug interaction (DDI) prevalence and examine longitudinal associations between DDI exposure and health outcomes (emergency department [ED] visits, quality‐of‐life [QoL] and functional decline) over approximately 10‐years in the older community‐dwelling population in Ireland.
John E. Hughes, Caitriona Cahir, Kathleen E. Bennett   +2 more
wiley   +1 more source

When the U Wave Tells the Story: Andersen–Tawil Syndrome Unmasked

Annals of Noninvasive Electrocardiology, Volume 30, Issue 6, November 2025.
Recurrent syncope in a young woman was diagnosed as Andersen‐Tawil syndrome (ATS), characterized by prominent U waves and prolonged QTU intervals. Genetic testing confirmed a KCNJ2 mutation. Tailored treatment, including medication adjustments, led to symptom improvement, emphasizing the importance of accurate diagnosis and management in ATS.
Shasha Yu, Hang Lv
wiley   +1 more source

Fluconazole‐Induced Electrolyte Disturbances and Cardiac Toxicity in a CRRT‐Dependent Patient With Acute Renal Failure

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Fluconazole is a commonly used antifungal drug in clinical practice. Both hyperkalemia and QT interval prolongation are life‐threatening complications of fluconazole. Our report warns clinicians to pay attention to the cardiotoxicity and electrolyte disorders of fluconazole when using it to avoid serious consequences.
Fuxia Jian, YuShan Zhang, Shili Zhong, Zhen Wang, Cui Shang   +4 more
wiley   +1 more source

Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue

Nature Communications, 2017
Torsade de Pointes (TdP) is a life-threatening ventricular arrhythmia often caused by drugs. In response to an urgent need for human tissue TdP models, here the authors describe a 3D human iPS cell-engineered heart tissue that generates TdP in response ...
Masahide Kawatou, Hidetoshi Masumoto, Hiroyuki Fukushima, Gaku Morinaga, Ryuzo Sakata, Takashi Ashihara, Jun K. Yamashita   +6 more
doaj   +1 more source

Case Report of Long QT Syndrome in a Patient With Syncope

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chun‐Yu Chen, Rui‐Xian Wang, Ken‐Pen Weng, Shih‐Ming Huang   +3 more
wiley   +1 more source