Results 91 to 100 of about 14,335 (221)

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1385-1396, May 2026.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Establishing gold standard approaches to rapid tranquillisation: a review and discussion of the evidence on the safety and efficacy of medications currently used [PDF]

open access: yes, 2008
Background: Rapid tranquillisation is used when control of agitation, aggression or excitement is required. Throughout the UK there is no consensus over the choice of drugs to be used as first line treatment.
Branford, David   +5 more
core   +1 more source

Machine Learning‐Based Prediction of Drug‐Induced QTc Changes in a Large Finnish Biobank Cohort

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Prolongation of the QT interval is a known precursor to serious arrhythmias and sudden cardiac death, often triggered by medication use. Current medication risk evaluation platforms rely on literature‐based synthesis and may lag behind real‐world developments.
Ville Langén   +7 more
wiley   +1 more source

Sleep-Associated Torsades de Pointes: A Case Report

open access: yesClinical Practice and Cases in Emergency Medicine, 2017
Torsades de Pointes (TdP) is a polymorphic ventricular tachycardia that occurs in the presence of an acquired or congenital long QT syndrome (LQTS). We present the case of a 57 year-old man with end-stage renal disease on methadone maintenance in which ...
Guy Carmelli, Ian S. deSouza
doaj   +1 more source

Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
This review presents a process‐oriented framework for vascularized cardiac tissue engineering, highlighting how the coordinated design of cells, biomaterials, and biofabrication strategies enables the functional development or vascularized myocardium for disease modelling and drug discovery.
Yang Liu   +9 more
wiley   +1 more source

Torsade de Pointes Induced by Hypokalemia from Imipenem and Piperacillin

open access: yesCase Reports in Cardiology, 2017
Imipenem-cilastatin and piperacillin-tazobactam are two antibiotics with broad antimicrobial coverage. Besides the many well established adverse effects of these drugs, there have been few case reports of hypokalemia.
Varun Kumar   +2 more
doaj   +1 more source

Torsades de Pointes associated with QT prolongation after catheter ablation of paroxysmal atrial fibrillation

open access: yesIndian Pacing and Electrophysiology Journal, 2017
A 79-year-old woman who underwent catheter ablation for paroxysmal atrial fibrillation presented with Torsades de Pointes (TdP). Aggravation of prolonged QT interval which is most likely due to neural modulation by catheter ablation, played major role in
Yae Min Park   +6 more
doaj   +1 more source

Интервал QT в кардиологической клинике [PDF]

open access: yes, 2011
Вісник Харківського національного університету імені В. Н. Каразіна, серія «Медицина». – 2009. – № 879. – Випуск 18. – С. 73-96.Интервал QT, отражающий процессы деполяризации и реполяризации миокарда и, в конечном итоге, функцию изгнания желудочков ...
Кулик, В.Л.   +1 more
core  

Causal AI in Cardiac Arrhythmia: From Pattern Recognition to Mechanistic Insight

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
Causal artificial intelligence (AI) in Cardiac Arrhythmia: From Pattern Recognition to Mechanistic Insight. Multimodal cardiac data, including electrocardiograms (ECG), wearable device recordings, cardiac imaging, genetic information, and electronic health records, are integrated to support AI‐based analysis. Traditional AI approaches primarily rely on
Bara AbuBaha   +11 more
wiley   +1 more source

QTc Interval Prolongation and Associated Drug Therapy in Hospitalized Older Adults

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Francesco Fantin   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy