Results 81 to 90 of about 14,335 (221)
Amiodarone: Is it Safe in Stress Cardiomyopathy?
Amiodarone is a broad-spectrum antiarrhythmic agent used in day-to-day practice to treat ventricular tachycardia (VT) and supraventricular tachycardias like atrial flutter/atrial fibrillation.
Manisha Sreeramdass +2 more
doaj +1 more source
Rabbit models of heart disease. [PDF]
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
The first experience of implanted cardioverter/ defibrillator in a patient with life-threatening torsades de pointes.
E. V. Kolpakov +3 more
doaj
Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]
Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core
Drugs and life-threatening ventricular arrhythmia risk: results from the DARE study cohort. [PDF]
OBJECTIVES: To establish a unique sample of proarrhythmia cases, determine the characteristics of cases and estimate the contribution of individual drugs to the incidence of proarrhythmia within these cases.
Behr, ER +5 more
core +1 more source
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Pheochromocytoma patients can rarely have prolonged QT interval in the ECG. We report three cases of pheochromocytoma in females presenting with ventricular arrhythmia; two had torsades de pointes and a third patient had frequent VPCs and nonsustained ...
Sai Satish Oruganti
doaj +1 more source
Initiation and dynamics of a spiral wave around an ionic heterogeneity in a model for human cardiac tissue [PDF]
In relation to cardiac arrhythmias, heterogeneity of cardiac tissue is one of the most important factors underlying the onset of spiral waves and determining their type.
Dawyndt, Peter +2 more
core +2 more sources
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley +1 more source

