Results 61 to 70 of about 7,771 (181)

Torsade de Pointes Induced by Hypokalemia from Imipenem and Piperacillin

Case Reports in Cardiology, 2017
Imipenem-cilastatin and piperacillin-tazobactam are two antibiotics with broad antimicrobial coverage. Besides the many well established adverse effects of these drugs, there have been few case reports of hypokalemia.
Varun Kumar, Sandeep Khosla, Monica Stancu   +2 more
doaj   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, Volume 183, Issue 16, Page 4646-4662, August 2026.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Epicardial adipose tissue‐linked leukotriene and cytokine signalling pathways – novel targets for prevention of obesity‐ and diabetes‐linked ventricular arrhythmia

The Journal of Physiology, EarlyView.
Kelly A. Aromolaran, Ademuyiwa S. Aromolaran   +1 more
wiley   +1 more source

Methadone-induced Torsades de Pointes Masquerading as Seizures

Clinical Practice and Cases in Emergency Medicine, 2017
The authors herein present the case of a 53-year-old female who was being treated as an outpatient for seizure disorder but was also receiving high-dose methadone therapy.
David C. Traficante, Gordon Feibish, John Kashani   +2 more
doaj   +1 more source

Effects of pH on Nifekalant-Induced Electrophysiological Change Assessed in the Langendorff Heart Model of Guinea Pigs

Journal of Pharmacological Sciences, 2014
Since information regarding the effects of pH on the extent of nifekalant-induced repolarization delay and torsades de pointes remains limited, we assessed it with a Langendorff heart model of guinea pigs.
Katsuyuki Kazusa, Yuji Nakamura, Yudai Watanabe, Kentaro Ando, Atsushi Sugiyama   +4 more
doaj   +1 more source

Flecainide associated torsade de pointes: A potential case of reverse use dependence

Journal of Research in Medical Sciences, 2013
Flecainide has been known to cause torsades de pointes (TdP) in patients with structural heart disease and its mechanism has been attributed to use-dependency.
Kevin Hayes, Abhishek Deshmukh, Sadip Pant, Benjamin Culp, James Marsh, Hakan Paydak   +5 more
doaj  

Effect of intravenous ondansetron on QT interval prolongation in patients with cardiovascular disease and additional risk factors for torsades: a prospective, observational study

Drug, Healthcare and Patient Safety, 2011
Matthew J Hafermann1, Rocsanna Namdar2, Gretchen E Seibold2,3, Robert Lee Page 2nd2,31University of Washington Medical Center, Department of Pharmacy, Seattle, WA; 2University of Colorado Anschutz Medical Campus, School of Pharmacy, Aurora, CO ...
Hafermann MJ, Namdar R, Seibold GE, Page RL 2nd   +3 more
doaj  

TORSADES DE POINTES IN A PATIENT WITH HIV WHO ABANDONED TREATMENT: AN ATYPICAL PRESENTATION

Brazilian Journal of Infectious Diseases
Introduction: Torsades de Pointes (TdP) is a rare but potentially fatal form of polymorphic ventricular tachycardia associated with QT interval prolongation, with an estimated annual incidence of 0.16% and mortality of up to 20%.
Matheus da Silva Raetano, Kawã Maicky Aguiar Rodrigues, Danillo Batista Silveira, Cassia Fernanda Estofolete, Irineu Luiz Maia   +4 more
doaj   +1 more source

Dilated Cardiomyopathy Compatible With Sarcoidosis Presenting with Syncope Due to Torsades de Pointes: a Case Report

Journal of Cardiac Arrhythmias, 2020
Sarcoidosis is a multisystemic noncaseating granulomatous disease of unknown etiology. Cardiac sarcoidosis clinical presentation is diverse, and syncope is one of the possible primary events.
Carollina Fernandes Tinoco, Nathalia Rodrigues Perrenoud Branca, Gabriela Domingues Carvalho, Lívia Silva de Paula Faria, Erivelton Alessandro do Nascimento   +4 more
doaj  

Síndrome de QT largo y torsades de pointes tras la administración de levofloxacino

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2013
Aunque hay fármacos que producen una mínima prolongación del intervalo QT, éstos pueden inducir arritmias en combinación con otros que también prolonguen el intervalo QT o interfieran en su degradación.
Ignacio González Almarcegui, Leticia Fernández Salvatierra, Carolina I. Fuertes Schott, Sheila Sanz de Galdeano Delgado, Estela Val Jordan, Patricia Mora Rangil   +5 more
doaj