Results 41 to 50 of about 14,335 (221)

Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]

, 2020
Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Friedman, Ari B., Rischall, Megan L., Smith, Stephen W.   +2 more
core  

Solifenacin linked QT interval prolongation and torsades de pointes [PDF]

, 2017
[no ...
Bray, Jonathan, Hancox, Jules
core   +2 more sources

Systems Pharmacology [PDF]

, 2008
The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
core   +2 more sources

Ondansetron induced torsades de pointes

Clinical Case Reports, 2019
A single dose of oral Ondansetron can precipitate torsades de pointes and other arrhythmias in patients with risk factors that may prolong QTc interval.
Eshan Patel, Danielle Rosemond, Ashwad Afzal   +2 more
doaj   +1 more source

Methadone and Corrected QT Prolongation in Pain and Palliative Care Patients: A Case–Control Study [PDF]

, 2017
Background: Methadone (ME) is commonly used in pain and palliative care (PPC) patients with refractory pain or intolerable opioid adverse effects (AEs).
Brown, Jack, Hutchinson, David, Juba, Katherine, Khadem, Tina M.   +3 more
core   +2 more sources

Severe hypomagnesemia with secondary hypocalcaemia (HSH) presenting as recurrent self terminating Torsades de pointes

IHJ Cardiovascular Case Reports, 2020
Torsades de Pointes (TdP) is a potentially fatal cardiac arrhythmia, defined as the combination of polymorphic ventricular tachycardia with prolonged QT-interval. Hypomagnesemia of any cause can predispose to TdP.
Manjappa Mahadevappa, MD, DM,, Prashanth Kulkarni, MD, DM,, Pushpa NB, MBBS, MD,, Poornima KS, MBBS, PGDCC,   +3 more
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome

Case Reports in Medicine, 2014
We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose.
Paul Singh, J. Martin Maldonado-Duran
doaj   +1 more source

Torsades De Pointes Electrical Storm Induced by H1N1 in a Patient with KCNH2 Variant of Unknown Significance

Case Reports in Cardiology, 2020
This report describes a case of an electrical storm of Torsades De Pointes in a structurally normal heart, following an H1N1 infection in the presence of a genetic variant of unknown significance.
Bashar Khiatah, Jonathan Dukes, Christina Desai, Amanda Frugoli   +3 more
doaj   +1 more source

A Novel Frameshift Mutation, KCNH2 [p.Asp896ArgfsX79], Leading to Malignant Ventricular Arrhythmia, Identified After Treatment of Gastrointestinal BleedingNovel Teaching Points

CJC Open, 2021
A novel frameshift mutation in the KCNH2 gene for long QT syndrome type 2 (LQTS2) was identified after torsades des pointes ventricular tachycardia in a 49-year-old patient managed with octreotide and nadolol for an acute variceal bleed.
Wan Cheol Kim, MD, FRCPC, Edmond Lemire, MD, PhD, FRCPC, FCCMG, Siddarth Nosib, BSc, Shravankumar Nosib, MD, FRCPC   +3 more
doaj   +1 more source