Results 31 to 40 of about 466,154 (153)

Ondansetron induced torsades de pointes

Clinical Case Reports, 2019
A single dose of oral Ondansetron can precipitate torsades de pointes and other arrhythmias in patients with risk factors that may prolong QTc interval.
Eshan Patel, Danielle Rosemond, Ashwad Afzal   +2 more
doaj   +1 more source

A Novel Frameshift Mutation, KCNH2 [p.Asp896ArgfsX79], Leading to Malignant Ventricular Arrhythmia, Identified After Treatment of Gastrointestinal BleedingNovel Teaching Points

CJC Open, 2021
A novel frameshift mutation in the KCNH2 gene for long QT syndrome type 2 (LQTS2) was identified after torsades des pointes ventricular tachycardia in a 49-year-old patient managed with octreotide and nadolol for an acute variceal bleed.
Wan Cheol Kim, MD, FRCPC, Edmond Lemire, MD, PhD, FRCPC, FCCMG, Siddarth Nosib, BSc, Shravankumar Nosib, MD, FRCPC   +3 more
doaj   +1 more source

Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome

Case Reports in Medicine, 2014
We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose.
Paul Singh, J. Martin Maldonado-Duran
doaj   +1 more source

Severe hypomagnesemia with secondary hypocalcaemia (HSH) presenting as recurrent self terminating Torsades de pointes

IHJ Cardiovascular Case Reports, 2020
Torsades de Pointes (TdP) is a potentially fatal cardiac arrhythmia, defined as the combination of polymorphic ventricular tachycardia with prolonged QT-interval. Hypomagnesemia of any cause can predispose to TdP.
Manjappa Mahadevappa, MD, DM,, Prashanth Kulkarni, MD, DM,, Pushpa NB, MBBS, MD,, Poornima KS, MBBS, PGDCC,   +3 more
doaj   +1 more source

Loperamide Induced Torsades de Pointes: A Case Report and Review of the Literature

Case Reports in Medicine, 2016
Abuse of over the counter drugs often gets overlooked by health care providers. Loperamide is one such over the counter drug that is often abused by drug addicts.
O. Mukarram, Y. Hindi, G. Catalasan, J. Ward, Alexander Bauer   +4 more
semanticscholar   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Torsades de Pointes after Ondansetron Infusion in 2 Patients.

Texas Heart Institute Journal, 2017
Drugs that prolong the electrocardiographic QT interval increase the risk of ventricular arrhythmias, particularly torsades de pointes. Ondansetron, a 5-hydroxytryptamine type 3 receptor antagonist antiemetic, is one such drug.
Da-Young Lee, Tri Trinh, Sion K. Roy
semanticscholar   +1 more source

Global patterns of polypharmacy after acute heart failure hospitalization: Prevalence and outcomes from the REPORT‐HF registry

European Journal of Heart Failure, EarlyView.
Global patterns of polypharmacy after acute heart failure hospitalization. GDMT, guideline‐directed medical therapy; HF, heart failure. Aims Polypharmacy, defined as the concurrent use of ≥5 medications, is prevalent among older adults with heart failure (HF).
Wan Ting Tay, Tiew‐Hwa Katherine Teng, Wouter Ouwerkerk, John G.F. Cleland, Sean P. Collins, Christiane E. Angermann, Kenneth Dickstein, Ulf Dahlstrom, Anja Schweizer, Achim Obergfell, Kai‐Hang Yiu, Mathieu Ghadanfar, Mahmoud Hassanein, Qing‐Wen Ren, Wen‐Li Gu, Georg Ertl, Sergio V. Perrone, Gerasimos Filippatos, Carolyn S.P. Lam, Jasper Tromp   +19 more
wiley   +1 more source

Marked QTc Prolongation and Torsades de pointes in Patients with Chronic Inflammatory Arthritis

Frontiers in Cardiovascular Medicine, 2016
Mounting evidence indicates that in chronic inflammatory arthritis (CIA), QTc prolongation is frequent and correlates with systemic inflammatory activation.
P. Lazzerini, P. Capecchi, I. Bertolozzi, G. Morozzi, S. Lorenzini, A. Simpatico, E. Selvi, M. Bacarelli, M. Acampa, Deana Lazaro, N. El-Sherif, M. Boutjdir, F. Laghi-Pasini   +12 more
semanticscholar   +1 more source

Torsades De Pointes Electrical Storm Induced by H1N1 in a Patient with KCNH2 Variant of Unknown Significance

Case Reports in Cardiology, 2020
This report describes a case of an electrical storm of Torsades De Pointes in a structurally normal heart, following an H1N1 infection in the presence of a genetic variant of unknown significance.
Bashar Khiatah, Jonathan Dukes, Christina Desai, Amanda Frugoli   +3 more
doaj   +1 more source