Results 71 to 80 of about 5,537 (272)

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

A study of 23 dairy cows with post‐partum uterine torsion

open access: yesVeterinary Medicine and Science
Background Uterine torsion in dairy cows generally occurs during gestation. However, some cows develop uterine torsion after calving, and the details of which are not known.
Kei Kazama   +3 more
doaj   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

Phase-Field Simulation of Abnormal/Normal Recrystallization Kinetics in Ultrafine-Grained Aluminum Processed by High-Pressure Torsion Extrusion

open access: green, 2023
Olena Abramova   +7 more
openalex   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

CHARACTERISTICS OF TESTICULAR TORSION IN ARIFIN ACHMAD REGIONAL GENERAL HOSPITAL, PEKANBARU, RIAU PROVINCE, INDONESIA

open access: yesNational Journal of Medical Research, 2018
Background: Testicular torsion is an abnormality disease in the testicle because torsion of the spermatic cord resulting in occlusion and strangulation vascularization of the veins and arteries to the testes and epididymis.
Zuhirman Zamzami, Yenri Yunfaista
doaj  

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

Torsion of the Spermatic Cord: Is Bilateral Orchidopexy Really Necessary?

open access: yesInternational Journal of Medicine and Health Development, 2003
Aim: To evaluate the rationale for bilateral orchidopexy as treatment for unilateral torsion of the testis, by determining how frequently the contralateral testis shows an abnormal pathology in unilateral testicular torsion. Patients and Methods: This is
Anselem O Obi, Aloy E Aghaji
doaj  

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