Results 101 to 110 of about 1,146,764 (302)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Skeletal Muscle Mass Measured Noninvasively by D3-Creatine Dilution in Children and Term Infants

open access: yesJournal of Pediatrics: Clinical Practice
Objective: To measure the longitudinal changes in body composition including muscle mass (MM), total body water (TBW), and body fat in term infants and children using the D3Creatine (D3Cr) dilution method combined with 2H2O.
Mahalakshmi Shankaran, PhD   +8 more
doaj   +1 more source

Estimating total body water in neonates [PDF]

open access: yesArchives of Disease in Childhood - Fetal and Neonatal Edition, 1998
Editor—The body weight of the preterm babies in the study by Tang et al predicted the total body water better than any other single anthropomorphic measure, and that it accounted for 99% of the variations seen in body water measurements.1 The authors then used a variety of other measurements and anthropomorphic characteristics and combined them in a ...
openaire   +1 more source

Influence of posture and frequency modes in total body water estimation using bioelectrical impedance spectroscopy in boys and adult males [PDF]

open access: yes, 2014
The aim of the study was to examine differences in total body water (TBW) measured using single-frequency (SF) and multi-frequency (MF) modes of bioelectrical impedance spectroscopy (BIS) in children and adults measured in different postures using the ...
Masaharu Kagawa   +8 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Sand Creek Watershed Project / Sand Creek Watershed Management Plan

open access: yes, 2003
The overall goal of the Sand Creek Watershed Project is to improve and protect the designated uses of the watershed. In order to achieve this overall goal and attain compliance with the TMDL established in Sand Creek, four goals have been established ...
Annis Water Research Institute
core  

Total Body Water and Body Composition in Phalaropes and Other Birds

open access: yes, 1991
Contrary to some reviews, total body water (TBW) may fall below the expected value of about 65% in birds if measured as a percentage of total body mass.
Jehl, Joseph R, Jr, Ellis, Hugh I
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil

open access: yes, 2003
Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Wells, J.C.K., Treleaven, P., Cole, T.J.
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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