Results 131 to 140 of about 688,578 (316)
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang +17 more
wiley +1 more source
High serum total cholesterol; an indicator for monitoring cholesterol lowering efforts : U.S. adults, 2005-2006 [PDF]
"Elevated serum total cholesterol is a major and modifiable risk factor for heart disease, the lead-ing cause of death in the United States (1,2).
core
Oncentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol"http://www ...
Christian Herder (44905) +9 more
core +1 more source
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Xis indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905) +9 more
core +1 more source
Yongkang Liu,1 Cuiping Yuan,1 Xiao Chen,1 Xiaokun Fang,1 Jingru Hao,1 Maodong Zhou,1 Xin Sun,1 Minghua Wu,2 Zhongqiu Wang1 1Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, People’s Republic of ...
Liu Y +8 more
doaj
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Is indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905) +9 more
core +1 more source
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
Preparation and some properties of cholesterol oxidase from Rhodococcus sp. R14-2
Rhodococcus sp. R14-2, isolated from Chinese Jin-hua ham, produces a novel extracellular cholesterol oxidase (COX). The enzyme was extracted from fermentation broth and purified 53.1-fold based on specific activity.
Wang, C.T. +6 more
core +1 more source

