Results 141 to 150 of about 690,603 (361)
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
, 2011 Xis indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905) +9 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
, 2011 An increased plasma cholesterol concentration is associated with increased risk of cardiovascular disease. However, individuals vary largely in their response to cholesterol lowering drugs and 40% of them, do not reach their cholesterol-lowering target.
van de Pas, N., Pas, N., van de
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, 2011 Ncentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol"http://www ...
Christian Herder (44905) +9 more
core +1 more source
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
Total and high-density lipoprotein cholesterol in adults; National Health and Nutrition Examination Survey, 2009-2010 [PDF]
The percentage of adults aged 20 and over with high total cholesterol has declined substantially since 1999\u20132000. For 2009\u20132010, the percentage of adults with high total cholesterol was 13.4%, thus meeting the Healthy People 2010 target of 17 ...
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Advanced Science, EarlyView.Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Total and High-Density Lipoprotein Cholesterol in Adults: United States, August 2021- August 2023 [PDF]
This report presents prevalence of high total cholesterol and low high-density lipoprotein cholesterol by sex and age group for adults age 20 and older from the August 2021\u2013August 2023 National Health and Nutrition Examination ...
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