Results 121 to 130 of about 7,360,049 (312)

Association of Plasma Lipids with White Matter Hyperintensities in Patients with Acute Ischemic Stroke

International Journal of General Medicine, 2023
Yongkang Liu,1 Cuiping Yuan,1 Xiao Chen,1 Xiaokun Fang,1 Jingru Hao,1 Maodong Zhou,1 Xin Sun,1 Minghua Wu,2 Zhongqiu Wang1 1Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, People’s Republic of ...
Liu Y, Yuan C, Chen X, Fang X, Hao J, Zhou M, Sun X, Wu M, Wang Z   +8 more
doaj  

Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol-12

, 2011
Ncentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol"http://www ...
Christian Herder (44905), Thomas Illig (44906), Melanie Kolz (44899), Martina Müller (44900), Natalie Khuseyinova (44901), Christine Meisinger (44904), Barbara Thorand (44903), Jens Baumert (39941), Wolfgang Koenig (26222), Norman Klopp (44902)   +9 more
core   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

High serum total cholesterol; an indicator for monitoring cholesterol lowering efforts : U.S. adults, 2005-2006 [PDF]

"Elevated serum total cholesterol is a major and modifiable risk factor for heart disease, the lead-ing cause of death in the United States (1,2).

core  

Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol-3

, 2011
Xis indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905), Thomas Illig (44906), Melanie Kolz (44899), Martina Müller (44900), Natalie Khuseyinova (44901), Christine Meisinger (44904), Barbara Thorand (44903), Jens Baumert (39941), Wolfgang Koenig (26222), Norman Klopp (44902)   +9 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol-1

, 2011
Xis indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905), Thomas Illig (44906), Melanie Kolz (44899), Martina Müller (44900), Natalie Khuseyinova (44901), Christine Meisinger (44904), Barbara Thorand (44903), Jens Baumert (39941), Wolfgang Koenig (26222), Norman Klopp (44902)   +9 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol-9

, 2011
Xis indicate TC/HDL-C concentrations of patients with at least one copy of the minor allele.Copyright information:Taken from "Association between variations in the gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL ...
Christian Herder (44905), Thomas Illig (44906), Melanie Kolz (44899), Martina Müller (44900), Natalie Khuseyinova (44901), Christine Meisinger (44904), Barbara Thorand (44903), Jens Baumert (39941), Wolfgang Koenig (26222), Norman Klopp (44902)   +9 more
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source