Results 121 to 130 of about 17,532,710 (263)
Tsui Hark is a prolific Chinese film director, writer and producer with over 100 credits to his name. He founded the successful Film Workshop production company with his wife, Nansun Shi, in 1984. He has directed such titles as Zu Warriors from the Magic
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Wake In Fright (1971) is a film directed by Ted Kotcheff. The film relates the story of a teacher en route to Sydney whose life is hijacked by the debauchery of nights spent in the menacing outback mining town of Bundanyabba.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Berthold Wolpe: The Total Man [Collection]
, 2018 Phil Cleaver’s research on Berthold Wolpe (1905-1989) contributes uniquely to a growing body of work that examines the legacy of the German-Jewish designer, typographer and illustrator.
Cleaver, P.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Wayne Levy Film and Television Soundtrack Collection
A number of soundtracks for films and television shows were donated to the AFI Research Collection by the estate of Wayne Levy. The soundtracks are mainly on vinyl LPs, featuring films and TV shows from the 1970s and 80s. It is mainly Australian material,
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source