Results 101 to 110 of about 17,532,710 (263)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Original Newspaper Collection

open access: yes
The Original Newspaper Collection has a growing collection of newspaper titles. The majority of the newspapers date from the 19th and 20th centuries; however, a select few date back to the 18th century. Many of the newspapers were published in Baltimore,
Original Newspaper Collection
core  

Baltimore Smallpox Epidemic Collection

open access: yes, 1871
The Baltimore Smallpox Epidemic Collection comprises correspondence and financial records relating to an epidemic between 1871 and 1882. Topics of interest include smallpox vaccinations, measures taken to prevent the spread of the epidemic, including ...
Baltimore Smallpox Epidemic Collection
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Automating Registry Data Collection of Total Ankle Arthroplasty Complications Using Artificial Intelligence: A Pilot Study

open access: yesFoot & Ankle Orthopaedics
Research Type: Level 3 - Retrospective cohort study, Case-control study, Meta-analysis of Level 3 studies Introduction/Purpose: Identifying and tracking surgical complications is a critical component of maintaining quality registries and improving ...
Michael Hewitt BA   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

United Kingdom Cinema of the 1960s Collection

open access: yes
This collection of items held by the AFI Research Collection relates to various aspects of United Kingdom cinema and television in the 1960s. The majority of the 100+ items held are clippings files and journal articles on United Kingdom films.

core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A Qualitative Study of Discharge Waste Water from Babil / 2 Batteries Factory in Baghdad

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
 The quality of industrial water from (Babil / 2 batteries factory in Baghdad) was  investigated, and evaluated the physical and chemical characteristics of the water discharged from sections ALShahen , final collection sank. The values were represented
Suhair A. Musa, Manal M.AL-Musawi
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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