Results 231 to 240 of about 17,532,710 (263)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Construction of nursing-sensitive quality indicators for hemodialysis vascular access: a Delphi study. [PDF]

Front Public Health
Zhang Y, He L, Tang S, Gao Y, Chen H, Shi M, Chen L.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Effects of increasing doses of wood vinegar on feed intake, digestibility, ingestive behavior, nitrogen balance and serum biochemistry in sheep. [PDF]

Vet Anim Sci
Nogueira MACS, Silva EMN, Oliveira MMG, Costa RMND, Silva EAD, Freitas RS, Bezerra MG, Almeida JGL, Araújo TLAC, Firmino SS, Pimenta AS, Lima Júnior DM.   +11 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The Impact of Collection Protocol on the Yield and Purity of Mesenchymal Stem Cell-Derived Extracellular Vesicles Isolated From Serum-Free Media. [PDF]

Biotechnol J
Phelps J, Tamrin SH, Duncan NA, Sen A.
europepmc   +1 more source

Fathers' attitudes toward breastfeeding, their participation, and influence: a cross-sectional study in Turkey. [PDF]

Int Breastfeed J
Bayrak Aykan E, Kırcı Temiz T.
europepmc   +1 more source

The relationship between information overload, adjustment to cancer, and level of health perception in patients with cancer: a descriptive cross-sectional study. [PDF]

Sao Paulo Med J
Tanriverdi Ö, Ayik DB.
europepmc   +1 more source

Associations between interpreter dependency and rehabilitation outcomes and care processes following acquired brain injury: a Swedish registry-based cohort study.

J Rehabil Med
Grut E, Blom Johansson M, Löfgren M.
europepmc   +1 more source