Results 251 to 260 of about 8,315,055 (305)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The prevalence of unclosed transverse foramina in the cervical spine of a South African population sample. [PDF]

Surg Radiol Anat
Nalla S, Noorbhai N, Paton GJ.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

New trends and hotspots in Sepsis-associated encephalopathy research: a bibliometric and visualization analysis. [PDF]

Front Aging Neurosci
Wang Y, Zheng L, Ye F.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Building Capacity in Institutional Operational Research in Low-Resource Settings: Protocol for an Implementation Research Study.

JMIR Res Protoc
Ali S, Murthy GVS, Bassett KL, Reddy P, Judson K, Gilbert SS, Patra A, Gudlavalleti AG, Mahapatra D, Pant H, Dakhwa P, Jameel S, Pandey SP, Tetali S, Chaudhuri S, Imandi S, Kamalakannan S.   +16 more
europepmc   +1 more source

Clinical, haematological, and biochemical responses of rectal oxygen-ozone administration in sheep. [PDF]

Vet Res Commun
Souza VRC, Carvalho RS, Coelho CS, Dâmaso Â.   +3 more
europepmc   +1 more source

The accuracy of a 4-item hydration self-assessment model to classify urine concentration using different cut-offs. [PDF]

Perform Nutr
Wardenaar FC, Schott KD, Seltzer RGN, Butterick B, Dow E, Kooima P, Freire R, Reid KD, Stow Z, Gopalakrishnan ST, Remington R, Sklar D, Gordon G, Ruby B, Burgess JL, Kavouras SA.   +15 more
europepmc   +1 more source

Dairy Sites with Milk Exposure Are Most Likely to Have Detection of Influenza A Virus. [PDF]

Microorganisms
Stenkamp-Strahm C, McCluskey B, Melody B, Urie N, Amey N, Lomkin R, Campbell AJ, Lakdawala S, Lombard J.   +8 more
europepmc   +1 more source