Results 81 to 90 of about 12,796 (264)
Augmenting graphs to partition their vertices into a total dominating set and an independent dominating set [PDF]
Opuscula MathematicaA graph \(G\) whose vertex set can be partitioned into a total dominating set and an independent dominating set is called a TI-graph. There exist infinite families of graphs that are not TI-graphs. We define the TI-augmentation number \(\operatorname{ti}(
Teresa W. Haynes, Michael A. Henning
doaj +1 more source
Computing locating-total domination number in some rotationally symmetric graphs. [PDF]
Sci Prog, 2021 Raza H, Iqbal N, Khan H, Botmart T.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Graphs whose vertex set can be partitioned into a total dominating set and an independent dominating set [PDF]
Opuscula MathematicaA graph \(G\) whose vertex set can be partitioned into a total dominating set and an independent dominating set is called a TI-graph. We give constructions that yield infinite families of graphs that are TI-graphs, as well as constructions that yield ...
Teresa W. Haynes, Michael A. Henning
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Total $k$-distance domination critical graphs [PDF]
Transactions on Combinatorics, 2016 A set $S$ of vertices in a graph $G=(V,E)$ is called a total$k$-distance dominating set if every vertex in $V$ is withindistance $k$ of a vertex in $S$.
Doost Ali Mojdeh +3 more
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source