Results 101 to 110 of about 11,484 (286)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
On computational and combinatorial properties of the total\n co-independent domination number of graphs [PDF]
, 2017 Abel Cabrera Martínez +3 more
openalex +2 more sources
Locating-Total Domination Number in Strong Product of Two Paths
, 2020 Wei Kang, Jianping Li, Zhemin Li
openalex +2 more sources
On the total restrained domination number of direct products of graphs [PDF]
, 2012 Hong-yu. Chen +3 more
openalex +1 more source
On Secure Total Domination Cover Pebbling Number
, 2022 S. Sarah Surya, Lian Mathew
openalex +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Relating the total domination number and the annihilation number for quasi-trees and some composite graphs [PDF]
, 2021 Hongbo Hua +3 more
openalex +1 more source
Total roman domination number of graphs
, 2022 In this paper a characterization of minimal total roman dominating functions has been proved. It has also been proved that if v is a pendant vertex and its neighbor u is not a pendant vertex then f(v) = 0 or 1 for any minimal total roman dominating function f. The operation of vertex removal has been considered.
Thakkar, Dineshbhai, Badiyani, Sanket
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source