Results 101 to 110 of about 195,942 (257)

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Risk-Based Gastrointestinal Parasite Control in a Tropical Zoological Institute

Journal of Zoological and Botanical Gardens
The surveillance and treatment of parasites are important features of preventative healthcare plans in zoological institutes. The parasite control strategies employed in temperate regions often involve prophylactic anthelmintic treatments during seasons ...
Yirui Heng, Delia Hwee Hoon Chua
doaj   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Avaliação das perdas endógenas e das exigências de fósforo, por meio da técnica da diluição isotópica, para suínos em crescimento Evaluation of endogenous fecal losses and of phosphorus requirements for swines in the growing phase based on isotopic dilution technique

Revista Brasileira de Zootecnia, 1999
Esta pesquisa foi realizada para determinar as perdas endógenas mínimas, as exigências nutricionais de fósforo (P) para mantença, a biodisponibilidade do P de fosfato bicálcico e a variação da concentração de P no plasma, em suínos de 20 kg PV. Os suínos
João Batista Lopes, Dorinha Miriam Silber S. Vitti, Agustinho Valente de Figueirêdo, Hacy Pinto Barbosa   +3 more
doaj   +1 more source

Association of intestinal alkaline phosphatase with necrotizing enterocolitis among premature infants [PDF]

, 2019
Importance: Necrotizing enterocolitis (NEC) in preterm infants is an often-fatal gastrointestinal tract emergency. A robust NEC biomarker that is not confounded by sepsis could improve bedside management, lead to lower morbidity and mortality, and permit
Barkemeyer, Brian, Buckley, Rebecca, Davis, Porcha, Fang, Zhide, Gerber, Zeromeh, Gong, Qingqing, Good, Misty, Heath, Maya, Kim, Sunyoung, Linneman, Laura, Penn, Duna   +10 more
core   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

The Effects of Microbial Additive Supplementation on Growth Performance, Blood Metabolites, Fecal Microflora, and Carcass Characteristics of Growing–Finishing Pigs

Animals
This study aimed to assess the effects of microbial additives that produce antimicrobial and digestive enzymes on the growth performance, blood metabolites, fecal microflora, and carcass characteristics of growing–finishing pigs.
Hyuk-Jun Lee, Bu-Gil Choi, Young-Ho Joo, Chang-Hyun Baeg, Ji-Yoon Kim, Dong-Hyeon Kim, Seong-Shin Lee, Sam-Churl Kim   +7 more
doaj   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Investigation and detection of multiple antibiotic-resistant pathogenic bacteria in municipal wastewater of Dhaka city

Discover Water
Background Water pollution in densely populated urban areas, mainly from municipal wastewater, poses a significant threat. Pathogenic bacteria, such as Vibrio spp. and fecal coliform, endanger public health and the environment.
Abu Bakkar Siddique, Atia Munni, Maruf Hasan, Rayhan Raj, Md. Abdul Mutalib, Md. Tajuddin Sikder, Tatsufumi Okino, Ayesha Ahmed, Md. Shakhaoat Hossain   +8 more
doaj   +1 more source