Results 141 to 150 of about 13,562,066 (260)

Mass balance study of [¹⁴C]-ABBV-552, a synaptic vesicle glycoprotein 2A positive modulator, in healthy male participants following single oral dose administration. [PDF]

Eur J Clin Pharmacol
Miles N, McNamee B, Soleman SI, Zadikoff C, Boiser J, Laplanche L, Burton R, Shebley M, Boinpally RR.   +8 more
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

A protocol for noninvasive quantification of dietary fat absorption in mice. [PDF]

STAR Protoc
Chan AP, Jarrett KE, Lai RW, Clifford BL, Williams KJ, Tarling EJ, de Aguiar Vallim TQ.   +6 more
europepmc   +1 more source

Tsui Hark Collection

Tsui Hark is a prolific Chinese film director, writer and producer with over 100 credits to his name. He founded the successful Film Workshop production company with his wife, Nansun Shi, in 1984. He has directed such titles as Zu Warriors from the Magic

core  

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

How can environmental fecal sampling support <i>Echinococcus multilocularis</i> surveillance in wild carnivores? [PDF]

Food Waterborne Parasitol
Wassermann J, Bussi M, Abs M, Kunisch AM, Oettler MJ, Krebs M, Rachel F, Heck J, Luttermann C, Schmüser H, Wernike K, Sauter-Louis C, Bergmann H, Schares GRM.   +13 more
europepmc   +1 more source

Rutgers University Research Data Collection

, 2011

core   +1 more source

Wake In Fright Collection

Wake In Fright (1971) is a film directed by Ted Kotcheff. The film relates the story of a teacher en route to Sydney whose life is hijacked by the debauchery of nights spent in the menacing outback mining town of Bundanyabba.

core  

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Human Disposition, Metabolism, and Excretion of Sevasemten (EDG-5506), a Selective Modulator of Fast Myosin in Healthy Volunteers. [PDF]

J Clin Pharmacol
Madden M, Evanchik M, Lane J, Donovan J, Russell AJ, Silverman JA.   +5 more
europepmc   +1 more source