Results 91 to 100 of about 2,253,480 (276)

On the Seidel spectrum of the total graphs of the rings of integers modulo n

Mathematics Open
In this paper, we study the Seidel spectrum of the total graph [Formula: see text] for various values of n. For [Formula: see text], with p prime, we give a complete spectral description and show that the spectrum is integral if and only if [Formula: see
Akhil P, Raisa DSouza
doaj   +1 more source

Total dominator chromatic number of a graph [PDF]

Transactions on Combinatorics, 2015
Given a graph $G$, the total dominator coloring problem seeks a proper coloring of $G$ with the additional property that every vertex in the graph is adjacent to all vertices of a color class. We seek to minimize the number of color classes.
Adel P. Kazemi
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Some totally modular cordial graphs

Discussiones Mathematicae Graph Theory, 2002
Two new labellings, total magic cordial and total sequential cordial labellings are defined. These are weaker version of magic and simply sequential labellings, respectively. The new requirement for labels is based on modulo 2 arithmetic. Several classes of graphs are studied.
openaire   +2 more sources

Totally Critical Even Order Graphs

Journal of Combinatorial Theory, Series B, 1999
A connected graph \(G\) is totally critical if its total chromatic number is at least two more than its maximum degree and is reduced by the removal of an arbitrary edge. Let \(G(p,q)\) have maximum degree \(\Delta(G)\); the deficiency of \(G\) is given by \(\text{def}(G)= \Delta(G)p- 2q\).
Hamilton, G.M., Hilton, A.J.W., Hind, H.R.F.   +2 more
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Total Cut Complexes of Graphs

Discrete & Computational Geometry
Inspired by work of Fröberg (1990), and Eagon and Reiner (1998), we define the \emph{total $k$-cut complex} of a graph $G$ to be the simplicial complex whose facets are the complements of independent sets of size $k$ in $G$. We study the homotopy types and combinatorial properties of total cut complexes for various families of graphs, including chordal
Margaret Bayer, Mark Denker, Marija Jelić Milutinović, Rowan Rowlands, Sheila Sundaram, Lei Xue   +5 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source