The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L+5 more
core +1 more source
HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou+7 more
wiley +1 more source
Clinical evaluation of repeated propofol total intravenous anesthesia in dog [PDF]
This current study designed to evaluate any possible changes in required doses and other cardiopulmonary findings after repeated propofol total intravenous anesthesia (TIVA) in dog.
Akhlaghi, Mreza.+4 more
core
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran+7 more
wiley +1 more source
Nerves and Anesthesia: A physics perspective on medicine [PDF]
We present a recent theory for nerve pulse propagation and anesthesia and argue that both nerve activity and the action of anesthetics can be understood on the basis of simple physical laws. It was found experimentally that biological membranes melt from a solid state to a liquid state just below physiological temperature. Such melting processes have a
arxiv
Intravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects. [PDF]
BACKGROUND AND OBJECTIVES: To describe the safety and tolerability of intravenous meloxicam compared with placebo across all phase II/III clinical trials.
Bergese, Sergio+7 more
core +1 more source
PIDA control of depth of hypnosis in total intravenous anesthesia [PDF]
In this paper we discuss the use of a Proportional-Integral-Derivative-Acceleration (PIDA) controller for the Depth-of-Hypnosis (DoH) control in total intravenous anesthesia (TIVA).
Milanesi, Marco+4 more
core +1 more source
This study presents engineered probiotics that convert immunosuppressive adenosine into inosine in tumors, alleviating immunosuppression and enhancing antitumor immunity. Demonstrating efficacy in murine ectopic and orthotopic tumor models, this approach offers a promising probiotic‐based cancer immunotherapy strategy, highlighting the potential of ...
Jinhui Wang+11 more
wiley +1 more source
Recovery after laparoscopic anesthesia: Three different anaesthesia techniques: Recovery after laparoscopic anesthesia [PDF]
A laparoscopic approach is commonly used for cholecystectomy today. Overall morbidity and mortality after this type of surgery depends on both surgical and anesthetic procedures, primarily from the choice of anesthesia technique and drugs throughout the ...
Boboš Marina+5 more
doaj
UWF-RI2FA: Generating Multi-frame Ultrawide-field Fluorescein Angiography from Ultrawide-field Retinal Imaging Improves Diabetic Retinopathy Stratification [PDF]
Ultrawide-field fluorescein angiography (UWF-FA) facilitates diabetic retinopathy (DR) detection by providing a clear visualization of peripheral retinal lesions. However, the intravenous dye injection with potential risks hamper its application. We aim to acquire dye-free UWF-FA images from noninvasive UWF retinal imaging (UWF-RI) using generative ...
arxiv