Results 151 to 160 of about 163,866 (351)

The free energy of biomembrane and nerve excitation and the role of anesthetics

, 2018
In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference ...
Heimburg, Thomas, Jackson, Andrew D., Music, Tea, Wang, Tian   +3 more
core   +1 more source

Development of Teleoperated Robotic System for Remote Intraocular Microsurgery

Advanced Science, EarlyView.
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu, Zhangkai Lian, Wenben Chen, Yanlin Li, Jiali Liu, Hongli Liang, Rihui Song, Zikai Lin, Mingyuan Li, Yining Huang, Ling Jin, Zheming Zhang, Xiaoyue Wei, Bingqian Liu, Wei Ma, Tao Li, Hang Shao, Wei Liu, Kun Gao, Xin Zhang, Pisong Yan, Ruiyang Li, Ruixin Wang, Xiaohang Wu, Duoru Lin, Xiang Chen, Jinghui Wang, Xingwu Zhong, Mohammad Ali Nasseri, Kai Huang, Haotian Lin   +30 more
wiley   +1 more source

Assessment of different anesthesia depth under total intravenous anesthesia on postoperative cognitive function in laparoscopic patients

, 2016
Aiqing Nie, Delin Zhang
openalex   +1 more source

Propofol-Based Total Intravenous Anesthesia is Associated with Better Survival than Desflurane Anesthesia in Epithelial Ovarian Cancer Surgery: A Retrospective Cohort Study [PDF]

, 2021
Wei‐Cheng Tseng, Meei‐Shyuan Lee, Ying‐Chih Lin, Hou‐Chuan Lai, Mu-Hsien Yu, Ke-Li Wu, Zhi‐Fu Wu   +6 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Designing the ideal perioperative pain management plan starts with multimodal analgesia. [PDF]

, 2018
Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while reducing individual class-related side effects ...
Mariano, Edward R., Schwenk, Eric S.
core   +1 more source

Prospect of Propofol-Total Intravenous Anesthesia

THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, 2007
弘前大学医学部附属病院では, 全身麻酔管理の80%以上にプロポフォールを主体にケタミンやフェンタニルを加えた全静脈麻酔法 (TIVA) を用いて施行している. TIVAにより, 地球温暖化やオゾン層破壊の原因となる亜酸化窒素や揮発性吸入麻酔薬の使用を減らすことができる. また, 現在までの研究報告をみると揮発性吸入麻酔薬が炎症促進作用を示すのに対し, 静脈麻酔薬プロポフォール, ケタミンは抗炎症効果を示す可能性が高い. また, プロポフォールにがん転移抑制効果があるのに対し, 揮発性吸入麻酔薬では転移を促進させるとする論文も発表されている. したがって, 環境に優しく侵襲防御に有利なプロポフォールを中心としたTIVAは, 今後さらに普及していくものと予測される.
openaire   +2 more sources

Postoperative nausea and vomiting after total thyroidectomy: sevoflurane combined with prophylactic ramosetron vs. propofol-based total intravenous anesthesia

, 2014
Sang Hee Park, Hyung Gon Lee, Chang Young Jeong, Seongwook Jeong, Seong Heon Lee, Hwi Jin Kim   +5 more
openalex   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source