Results 51 to 60 of about 81,269 (314)

A systematic review of the evidence for single stage and two stage revision of infected knee replacement [PDF]

open access: yes, 2013
BACKGROUND: Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements being implanted each year in the UK, periprosthetic infection (PJI) is set to ...
Reed, Mike R.   +5 more
core   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

open access: yesAdvanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin   +12 more
wiley   +1 more source

The Comparison of Computer Navigation and Robotic-assisted Total Knee Arthroplasty: A Review of Current Literature

open access: yesFormosan Journal of Musculoskeletal Disorders
This review aimed to assess the existing evidence regarding the comparison between robotic-assisted (RA) and computer navigation (CN) total knee arthroplasty (TKA). Our study commenced on August 25, 2023, utilizing a methodological approach that combined
Chia-Chun Hsia   +5 more
doaj   +1 more source

Methods for Improving Quadriceps Femoris Strength after Total Knee Arthroplasty

open access: yesReabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2019
Research background. The recovery of quadriceps femoris muscle strength after total knee arthroplasty is suboptimal. Quadriceps weakness is associated with decreased gait speed, balance, stair–climbing and chair rise ability, as well as increased risk ...
Toma Petkutė, Eglė Lendraitienė
doaj   +1 more source

Predicting dissatisfaction following total knee replacement:a prospective study of 1217 patients

open access: yes, 2010
Up to 20% of patients are not satisfied with the outcome following total knee replacement (TKR). This study investigated the pre- and post-operative predictors of dissatisfaction in a large cohort of patients undergoing TKR.
D. MacDonald   +11 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

The role of pain and function in determining patient satisfaction after total knee replacement - Data from the National Joint Registry for England and Wales

open access: yes, 2007
A postal questionnaire was sent to 10 000 patients more than one year after their total knee replacement (TKR). They were assessed using the Oxford knee score and were asked whether they were satisfied, unsure or unsatisfied with their TKR.
Gregg, PJ   +8 more
core   +1 more source

Preoperative Total Iron‐Binding Capacity Is a Novel Surrogate Marker of Short‐ and Long‐Term Outcomes After Liver Resection for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
HCC patients with low preoperative TIBC levels experienced significantly more frequent post‐hepatectomy complications. Furthermore, these patients were significantly correlated with worse survival. Preoperative serum TIBC levels may be a novel surrogate marker of postoperative complications and long‐term survival after hepatectomy.
Taishi Yamane   +9 more
wiley   +1 more source

Revision Total Knee Arthroplasty Using Robotic Arm Technology

open access: yesArthroplasty Today, 2022
Total knee arthroplasty (TKA) is a highly successful operation for the treatment of end-stage osteoarthritis of the knee. Increasing use of computer-assisted and robotic-assisted total joint arthroplasty has been shown to improve component position, with
Micah MacAskill, MD   +3 more
doaj   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

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