Results 101 to 110 of about 1,514,703 (285)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Deformation analysis by an improved similarity transformation

open access: yesApplied Computing and Geosciences
In this contribution, deformation analysis is rigorously performed by a non-linear 3-D similarity transformation. In contrast to traditional methods based on linear least-squares (LLS), here we solve a non-linear problem without any linearization.
Vahid Mahboub
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Cancerphobia: Electromagnetic Fields and Their Impact on Residential Loan Values [PDF]

open access: yes
This article provides a matrix representation of the adjustment grid estimator. From this representation, one can invoke the Gauss-Mrkov theorem to examine the efficiency of ordinary least squares (OLS) and the grid estimator that uses OLS estimates of ...
Donald R. Epley, James A. Bryant
core  

Analysis of solution of the least squares problem [PDF]

open access: yes, 1999
For the given data $(p_i,t_i,f_i),$ $i=1,ldots,m$, we consider the existence problem of the best parameter approximation of the exponential model function in the sense of ordinary least squares and total least squares.
D. Jukić, R. Scitovski
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Computational Experiments on the Tikhonov Regularization of the Total Least Squares Problem [PDF]

open access: yesComputer Science Journal of Moldova, 2009
In this paper we consider finding meaningful solutions of ill-conditioned overdetermined linear systems Ax≈b, where A and b are both contaminated by noise. This kind of problems frequently arise in discretization of certain integral equations. One of the
Maziar Salahi, Hossein Zareamoghaddam
doaj  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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