Results 61 to 70 of about 1,508,834 (285)

Improving Ensemble Forecasting Using Total Least Squares and Lead-Time Dependent Bias Correction

open access: yesAtmosphere, 2020
Numerical weather prediction (NWP) models produce a quantitative precipitation forecast (QPF), which is vital for a wide range of applications, especially for accurate flash flood forecasting.
Aida Jabbari, Deg-Hyo Bae
doaj   +1 more source

An adapted version of the element-wise weighted total least squares method for applications in chemometrics

open access: yes, 2007
The Maximum Likelihood PCA (MLPCA) method has been devised in chemometrics as a generalization of the well-known PCA method in order to derive consistent estimators in the presence of errors with known error distribution.
Markovsky, Ivan   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Use of Total Least Squares Adjustment in Geodetic Applications

open access: yesApplied Sciences
This article discusses the method of computing the values of the unknowns under the condition of the minimum sum of the squares of the residuals of the observations, also known as the least squares method, with the additional condition of taking into ...
Aleš Marjetič   +2 more
doaj   +1 more source

On weighted total least squares adjustment for solving the nonlinear problems

open access: yesJournal of Geodetic Science, 2014
In the classical geodetic data processing, a non- linear problem always can be converted to a linear least squares adjustment. However, the errors in Jacob matrix are often not being considered when using the least square method to estimate the optimal ...
Hu C., Chen Y., Peng Y.
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Sea Surface Temperature Retrieval from MODIS Radiances Using Truncated Total Least Squares with Multiple Channels and Parameters

open access: yesRemote Sensing, 2016
Global sea-surface temperatures (SST) from MODIS measured brightness temperatures generated using the regression methods, have been available to users for more than a decade, and are used extensively for a wide range of atmospheric and oceanic studies ...
Prabhat K. Koner, Andy Harris
doaj   +1 more source

Single-level resonance parameters fit nuclear cross-sections [PDF]

open access: yes, 1970
Least squares analyses of experimental differential cross-section data for the U-235 nucleus have yielded single level Breit-Wigner resonance parameters that fit, simultaneously, three nuclear cross sections of capture, fission, and ...
Drawbaugh, D. W.   +3 more
core   +1 more source

Scaled total least squares fundamentals [PDF]

open access: yesNumerische Mathematik, 2002
The authors analyse a particularly useful formulation of the scaled total least squares problem. The analysis is based on a new assumption that guarantees existence and uniqueness of meaningful solution for real positive parameters. The proposed in the paper theoretical considerations complex data are allowed.
Paige, Christopher C., Strakoš, Zdenek
openaire   +1 more source

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