Impact of total neoadjuvant therapy regimens on radiation-induced lymphopenia in locally advanced rectal cancer: a retrospective analysis. [PDF]
Sasaki R +11 more
europepmc +1 more source
ABSTRACT Background The expanding use of systemic therapies for recurrent and metastatic head and neck cancer has raised major concerns regarding affordability and equitable access, particularly across countries with differing income levels and health financing structures.
Arjun Gurmeet Singh +9 more
wiley +1 more source
Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer. [PDF]
Kagawa Y +5 more
europepmc +1 more source
Impact of Infratemporal Fossa Clearance on Survival in Advanced Buccal Mucosa Cancers
ABSTRACT Introduction Buccal mucosa cancers are the most prevalent oral cavity cancers in South Asia, often attributed to widespread tobacco use. The current NCCN guidelines generally advise against primary surgery for locally very advanced (cT4b) buccal cancers involving the masticatory space and infratemporal fossa (ITF).
Sudhir Nair +11 more
wiley +1 more source
Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient-centered approach that clusters two cohorts with different outcomes. [PDF]
Guadalajara H +14 more
europepmc +1 more source
What's New? Breast cancer incidence in women increases with age, but which subtypes contribute the most at different ages remains unclear. Incidence patterns of breast cancer subtypes are typically under‐reported in population‐based studies due to a high proportion of cases lacking subtype information.
Leo Gkekos +4 more
wiley +1 more source
Locoregional and systemic control after total neoadjuvant therapy with short-course radiotherapy for locally advanced rectal cancer: long-term outcomes from the LARCT-US study. [PDF]
Imam I +4 more
europepmc +1 more source
What's New? Colorectal cancer (CRC) recurrence is a significant threat to survival despite surgery with curative intent. The characteristics of CRC recurrence, however, remain poorly understood, challenging postoperative surveillance. This study investigated post‐recurrence mortality and associations between time‐to‐recurrence and mortality among stage
Jesper Nors +3 more
wiley +1 more source
Safety and efficacy of individualized modified total neoadjuvant therapy for low locally advanced rectal cancer. [PDF]
Ye Q +5 more
europepmc +1 more source
Total Neoadjuvant Therapy for Rectal Cancer: the Case Report
We report a case of advanced rectal cancer that could be radically resected after total neoadjuvant therapy (TNT). A 65-year-old man underwent TNT for lower rectal cancer. The patient received a short course of chemoradiation therapy (CRT) at a total dose of 30 Gy to the pelvic area, including lateral lymph nodes, in fractions of 3 Gy administered five
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