Results 51 to 60 of about 11,656,595 (311)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Evaluasi Karakteristik Fisik Kimiawi Perairan Situ Cibuntu, Kabupaten Bogor, Jawa Barat

Journal of Natural Resources and Environmental Management, 2021
Situ Cibuntu merupakan salah satu situ yang terletak di Kabupaten Bogor, Provinsi Jawa Barat. Situ Cibuntu yang memiliki luas permukaan 2,11 ha dengan kedalaman maksimum 1,20 m dimanfaatkan sebagai kolam retensi dan sarana pemancingan ikan. Perairan situ
Aiman Ibrahim, Siti Aisyah, Ira Akhdiana, Lukman, Aldiano Rahmadya, Novi Mayasari   +5 more
doaj   +1 more source

Determination of Total Nitrogen in Fertilizers

Journal of AOAC INTERNATIONAL, 1965
Abstract Five methods, AOAC 2.037, 2.039, modified reduced iron, chromium powder, and Raney nickel catalyst powder for the determination of total nitrogen in fertilizers, were submitted to collaborators for study. Twelve laboratories participated and completed the work. No one method was “best.” The modified reduced iron, chromium powder,
W E Urban, H A Davis
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Nitrogen use efficiency of silage corn with contrasting nitrogen fertility sources in a semi-arid system

Frontiers in Agronomy
Silage corn production in semi-arid environments poses challenges for sustainable intensification and soil health due to the removal of aboveground biomass during harvest.
Phearen Miller, Avneet Kakkar, Jeanette M. Norton   +2 more
doaj   +1 more source

Soil aggregate mediates the impacts of land uses on organic carbon, total nitrogen, and microbial activity in a Karst ecosystem

Scientific Reports, 2017
Understanding the effect of land use on soil carbon, nitrogen, and microbial activity associated with aggregates is critical for thorough comprehension of the C and N dynamics of karst landscapes/ecosystems.
Shuangshuang Xiao, Wei Zhang, Yingying Ye, Jie Zhao, Kelin Wang   +4 more
semanticscholar   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effect of fire severity on organic carbon, total nitrogen and available phosphorus of forest soils (Case study: Marivan) [PDF]

تحقیقات جنگل و صنوبر ایران, 2012
Fire is natural feature of most of ecosystems, including Mediterranean region and the site study in this research. In order to evaluate effect of fire intensity on dynamic of organic carbon, nitrogen and phosphorus of soil, 56 samples were selected from ...
Farzaneh Nazari, Vaheid Hosseini, Naghi Shabanian   +2 more
doaj   +1 more source