Results 41 to 50 of about 203,371 (261)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The Application of Potentiometric Methods in Determination Total Organic Carbon Content of Soil

International Journal on Advanced Science, Engineering and Information Technology, 2014
Potentiometric method is one method that is widely used to determine the content of certain ions in a solution, but have not been widely applied to the analysis of soil samples. In this research apply the potentiometric methods for the determination of total organic carbon content of solids affected by oil contamination using CO 2 selective electrode ...
Yohandri Bow, Hairul Hairul, Ibnu Hajar
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effects of Different Mulching Measures on Distribution of Organic Carbon and Inorganic Carbon in Soil Aggregates Under Spring Maize Cultivation

Shuitu baochi tongbao, 2023
[Objective] The effects of different mulching methods on the distribution of organic and inorganic carbon in soil aggregates on the Loess Plateau, and the mechanism under which soil aggregates sequester carbon under mulched conditions were determined in ...
Li Meng, Li Yan, Yang Na, Ma Zizong, Wang Hongli, Yue Shanchao, Zhai Bingnian, Wang Zhaohui, Li Ziyan   +8 more
doaj   +1 more source

Assessing Soil Functioning: What is the Added Value of Soil Organic Carbon Quality Measurements Alongside Total Organic Carbon Content?

Soil Biology and Biochemistry
Soil organic carbon (SOC) content is the most widely used soil health indicator, but many soil functions are also influenced by the quality of SOC. Yet, standardized SOC quality parameters that can be used in soil health assessments in addition to SOC content are still in development.
Koorneef, Guusje, Pulleman, Mirjam, Comans, Rob, van Rijssel, Sophie, Barré, Pierre, Baudin, François, de Goede, Ron   +6 more
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Source Rock Characteristic of Sargelu and Kurrachine Formations from the Selected Wells in Northern Iraq

Iraqi Geological Journal, 2021
A total of 56 cuttings samples of Sargelu and Kurrachine formations from different wells (Ain Zalah, Baiji, and Jabal Kand) in northern Iraq have been investigated in this study.
Arwa M. S. Al-Dolaimy
doaj   +1 more source

Total Organic Carbon and Total Nitrogen Contents in Lake Sediment as a Proxies of Paleoclimate

The Quaternary Research (Daiyonki-Kenkyu), 2003
湖沼堆積物中の全有機炭素(TOC)・全窒素(TN)含有率に関連する最近の研究を概観した.TOCおよびTNには,湖水中で自生するものと,陸上から運び込まれる外来性のものがあり,通常の調和型湖沼では前者を起源とするものが優占する.木崎湖における最近の研究では,1983年から1999年にかけての湖底堆積物中のTOC含有率は,同じ期間の湖水中の年間クロロフィルa量および冬の平均気温(12月～翌3月の平均)との間によい相関があることが認められた.このことは,気温が湖水中の生物生産性に影響を与えることを通じて,湖沼堆積物中への有機物流入を支配していることを意味する.野尻湖底堆積物のコア試料中のTOCとTNの含有率およびC/Nの変動を過去4.5万年間にわたって解析したところ ...
openaire   +2 more sources

INTERPRETING 14C AGES OF THE TOTAL ORGANIC CARBON CONTENT OF PREHISTORIC POTTERY

Радиоуглерод в археологии и палеоэкологии: прошлое, настоящее, будущее. Материалы международной конференции, посвященной 80-летию старшего научного сотрудника ИИМК РАН, кандидата химических наук Ганны Ивановны Зайцевой, 2020
Археологическая хронология для некоторых археологических памятников Восточной Европы основана в основ- ном на прямом керамики. Даты по пищевому нагару на сосудах также были получены, если это было возможно, но гораздо больше 14C датировок было получено по общего содержания органического углерода (TOCC) в че- репках.
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source