Results 51 to 60 of about 203,371 (261)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Carbon burial characteristics of Hongze Lake in the past 60 years

Shuiwen dizhi gongcheng dizhi
Lakes are important carbon sinks in terrestrial ecosystems. Currently, most of lake carbon burial research in China only considers organic carbon burial and has neglected inorganic carbon burial, which will lead to an underestimation of the total carbon ...
Jiahao QI, Taibei LIU, Hua ZHAO
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Nutrient Characteristics of Soil Aggregates in Larix gmelinii Plantations of Different Forest Ages from Seriously Burned Area in Great Khingan Mountains

Shuitu Baochi Xuebao
[Objective] In order to know the changes of nutrient content and distribution of soil aggregates under Larix gmelinii plantation of different forest ages after vegetation restoration in severely burned areas of Greater Khingan Mountains.
WEI Ziqiang, ZHENG Lei, HE Huaiyu, WANG Zhenguo, YI Huaihu, REN Peng, XIN Ying   +6 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The Stratification of Organic Carbon and Nitrogen in Top Soils as Affected by the Management of Organic and Conventional Rice Cultivation

Caraka Tani: Journal of Sustainable Agriculture, 2020
Organic and conventional management in rice cultivation have an impact on the nature of soil and the sustainability of agricultural system. This study aimed to determine the stratification of organic carbon and nitrogen in top soil from organic and ...
Arif Anshori, Ali Pramono, Mujiyo Mujiyo
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Changes in Mineralization Activity of Microbial Communities Depending on Physico-Chemical Properties of Soils and Cadmium Contamination [PDF]

Учёные записки Казанского университета: Серия Естественные науки, 2016
The effects of glucose and cadmium addition, as well as their combination on the CO2 efflux from soils, which differed by the total organic carbon content and texture, were studied.
A.R. Gilmullina, P.Y. Galitskaya , A.A. Saveliev, Y.V. Kuzyakov, S.Y. Selivanovskaya   +4 more
doaj