Results 151 to 160 of about 285,483 (304)

Autonomous linear lossless systems

open access: yes, 2008
We define a lossless autonomous system as one having a quadratic differential form associated with it called an energy function, which is positive and which is conserved.
Rao, Shodhan   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

KP solitons, total positivity, and cluster algebras

open access: yes, 2011
Soliton solutions of the KP equation have been studied since 1970, when Kadomtsev and Petviashvili [Kadomtsev BB, Petviashvili VI (1970) Sov Phys Dokl 15:539–541] proposed a two-dimensional nonlinear dispersive wave ...
Yuji Kodama, Lauren K. Williams
core   +1 more source

Contributing factors of health-related preventive behaviors among resident aliens in China

open access: yes环境与职业医学
BackgroundThe Belt and Road Initiative is promoting the growth of the cross-border population, and there is still a lack of study on modifiable factors associated with health-related preventive behaviors among resident aliens in China.
Jiayi LAI, Huishuan WU, Kezhi JIN
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Total positivity order and the normal distribution

open access: yes
Unlike the usual stochastic order, total positivity order is closed under conditioning. Here we provide a general formulation of the preservation properties of the order under conditioning; we study certain properties of the order including translation ...
Scarsini, Marco, Rinott, Yosef
core  

Total positivity in multivariate extremes

open access: yes, 2022
Positive dependence is present in many real world data sets and has appealing stochastic properties that can be exploited in statistical modeling and in estimation. In particular, the notion of multivariate total positivity of order 2 ($\text{MTP}_2$) is
Zwiernik, Piotr   +2 more
core  

Changes in positivity before and during the coronavirus disease 2019 pandemic and the potential influence of pandemic-related factors

open access: yesJournal of International Medical Research
Objective We aimed to compare Demodex positivity before and during the coronavirus disease 2019 pandemic. Methods Patients who underwent a standardized skin surface biopsy and direct microscopic examination for Demodex species in the prepandemic or ...
Ayşe Özkaçmaz   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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