Results 141 to 150 of about 285,483 (304)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Role of Colposcopy in Women with Normal Cytology and High-risk Human Papilloma Virus Positivity, Except for Types 16 and 18

open access: yesBagcilar Medical Bulletin
Objective: The main objective of present study was to evaluate the role of colposcopy in women with normal cytology and positivity for high risk human papilloma virus (HPV), except types 16 and 18.
Necim Yalçın   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Relationship between body positivity and body neutrality with body image, self-esteem, mindfulness and gratitude

open access: yesScientific Reports
Despite the growing popularity of body positivity and body neutrality on social media, their scientific differentiation remains unclear. Body positivity involves acceptance and a positive attitude toward one’s body regardless of societal ideals, whereas ...
Anna Lipińska
doaj   +1 more source

Characteristics of influenza virus epidemic in Yiwu City, Zhejiang Province from 2017 to 2022

open access: yesShanghai yufang yixue
ObjectiveTo investigate the epidemiological trends of influenza in Yiwu City, Zhejiang Province from 2017 to 2022, and to provide references for local adjustments to influenza prevention and control strategies.MethodsReal-time fluorescence quantitative ...
CHEN Buqing   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Seasonal distribution of total AES cases referred and arbovirus and scrub typhus positivity.

open access: yes, 2018
Seasonal distribution of total AES cases referred and arbovirus and scrub typhus positivity.
Devraj Sharma (5028716)   +8 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Total Positivity, Finite Reflection Groups, and a Formula of Harish-Chandra

open access: yes, 1995
Let W be a finite reflection (or Coxeter) group and K: R2 → R. We define the concept of total positivity for the function K with respect to the group W.
Gross, K.I., Richards, D.S.
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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