Results 131 to 140 of about 6,919,485 (295)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Positivity rate and percent of total positives by clinical indication.
, 2019 Positivity rate and percent of total positives by clinical indication.
Brittany Dyr (7164278) +6 more
core +1 more source
Permanental Inequalities for Totally Positive Matrices
The Electronic Journal of CombinatoricsWe characterize ratios of permanents of (generalized) submatrices which are bounded on the set of all totally positive matrices. This provides a permanental analog of results of Fallat, Gekhtman, and Johnson [Adv. Appl. Math. 30 (2003), 442-470] concerning ratios of matrix minors. We also extend work of Drake, Gerrish, and the first author [Electron. J.
Mark A. Skandera, Daniel Soskin
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
“BODY POSITIVITY" AND BODY IMAGE: POSITIVE AND NEGATIVE EFFECTS ON HEALTH
, 2022 reservedL’obiettivo di questa tesi è delineare il movimento del “body positivity” che, in seguito all’avvento dei social, sta crescendo esponenzialmente per contrastare gli ideali di bellezza imposti dalla società che vanno ad impattare sul benessere ...
ANTONELLO, NICOLA
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Prozac Leadership and the limits of positive thinking [PDF]
, 2012 This article critically examines excessive positivity in leadership dynamics. It argues that the tendency for leader positivity to become excessive is a recurrent but under-researched medium through which power and identity can be enacted in leadership ...
Collinson, David
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Bagcilar Medical BulletinObjective: The main objective of present study was to evaluate the role of colposcopy in women with normal cytology and positivity for high risk human papilloma virus (HPV), except types 16 and 18.
Necim Yalçın +5 more
doaj +1 more source