Results 131 to 140 of about 285,483 (304)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Total Positivity of Almost-Riordan Arrays
In this paper we study the total positivity of almost-Riordan arrays $(d(t)|\, g(t), f(t))$ and establish its necessary conditions and sufficient conditions, particularly, for some well used formal power series $d(t)$.
He, Tian-Xiao, Słowik, Roksana
core
Cone-theoretic generalization of total positivity
, 2012 This paper is devoted to the generalization of the theory of total positivity. We say that a linear operator A:Rn→Rn is generalized totally positive (GTP), if its jth exterior power ∧jA preserves a proper cone Kj⊂∧jRn for every j=1,…,n.
O.Y. Kushel, Kushel, O.Y.
core +1 more source
DiagnosticsObjectives: The main objective of the present study was to evaluate the outcomes of patients referred for colposcopy due to human papillomavirus (HPV) positivity and/or abnormal cytology.
Necim Yalcin +5 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Permanental Inequalities for Totally Positive Matrices
The Electronic Journal of CombinatoricsWe characterize ratios of permanents of (generalized) submatrices which are bounded on the set of all totally positive matrices. This provides a permanental analog of results of Fallat, Gekhtman, and Johnson [Adv. Appl. Math. 30 (2003), 442-470] concerning ratios of matrix minors. We also extend work of Drake, Gerrish, and the first author [Electron. J.
Mark A. Skandera, Daniel Soskin
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Total Positivity of Quasi-Riordan Arrays
In this paper the total positivity of quasi-Riordan arrays is investigated with use of the sequence characterization of quasi-Riordan arrays. Due to the correlation between quasi-Riordan arrays and Riordan arrays, this study is an in-depth discussion of ...
He, Tian-Xiao, Słowik, Roksana
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source