Results 121 to 130 of about 285,483 (304)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Current Status on the Epidemiology of Hepatitis B Virus Infection in İstanbul

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials
Introduction: Despite the availability of safe and effective vaccines against Hepatitis B virus (HBV), the infection remains a significant global health issue.
Mehmet Karabey   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Different reactive profiles of calmodulin in the CSF samples of Chinese patients of four types of genetic prion diseases

open access: yesFrontiers in Molecular Neuroscience
Background and purposeCalmodulin (CaM) levels exhibit significant elevation in the brain tissue of rodent and cell line models infected with prion, as well as in the cerebrospinal fluid (CSF) samples from patients diagnosed with sporadic Creutzfeldt ...
Xiao-Xi Jia   +15 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Tuberculin skin test results among student close contacts with pulmonary tuberculosis

open access: yes预防医学
Objective: To investigate the status of tuberculin skin test (TST) results and the influencing factors among student close contacts with pulmonary tuberculosis, so as to provide the evidence for developing prevention and control strategies for pulmonary ...
SUN Jiamei, LU Qiaoling, GAO Huaqiang, YANG Zuokai, XU Laichao
doaj   +1 more source

Total positivity of a Cauchy kernel

open access: yesJournal of Approximation Theory, 2014
We study the total positivity of the kernel $1/(x^2 + 2 \cos(π\a)xy +y^2).$ The case of infinite order is characterized by an application of Schoenberg's theorem. We then give necessary conditions for the cases of any given finite order with the help of Chebyshev polynomials of the second kind.
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Total positivity properties of Jacobi–Stirling numbers

open access: yes, 2012
The Jacobi–Stirling numbers of the first and second kinds were first introduced in Everitt et al. (2007) [8] and they are a generalization of the Legendre–Stirling numbers.
Mongelli, Pietro, Pietro Mongelli
core   +1 more source

Aggregatibacter Actinomycetemcomitans With Periodontitis and Rheumatoid Arthritis

open access: yesInternational Dental Journal
: Objective: The aim of this work was to explore the association between Aggregatibacter actinomycetemcomitans (A actinomycetemcomitans) infection and disease activity amongst those with rheumatoid arthritis (RA) with or without periodontitis (PD) in a ...
Yizhi Huang, Su Ni
doaj   +1 more source

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