Results 91 to 100 of about 2,153,594 (310)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2021 — Background: Negative pressure wound therapyhas proven to be an ecient tool in the provision of temporarywound coverage in cases where definitive primary woundcoverage is impossible.
Konečný, Jan +5 more
core +1 more source
Numerical Study of the Effect of using a Small Fence through the Flow Passage on the Performance of a Langston Turbine Cascade [PDF]
JES: Journal of Engineering SciencesThe present study computationally investigates the steady incompressible flow behavior through Langston turbine cascade. A three dimensional numerical model was developed by ANSYS-Fluent software.
Mostafa Kamal +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Sources of dietary protein and risk of hypertension in a general Dutch population
, 2012 Evidence suggests a small beneficial effect of dietary protein on blood pressure (BP), especially for plant protein. We examined the relationship between several types of dietary protein (total, plant, animal, dairy, meat and grain) and the risk of ...
Engberink, M.F. +4 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Acta Orthopaedica et Traumatologica Turcica, 2018 Objective: The aim of this study was to compare the limb occlusion pressure (LOP) determination and arterial occlusion pressure (AOP) estimation methods for tourniquet pressure setting in adult patients undergoing knee arthroplasty under combined spinal ...
Bahattin Tuncali +3 more
doaj +1 more source
Experimental Biology and Medicine, 1977 Materials and methodsInterstitial fluid pressure (Pif) of the dog was measured from capsules implanted in subcutaneous tissue of the upper and lower hindleg 4 to 8 weeks prior to use. (The capsules were a disk-shaped hollow (6 mm x 9 mm i.d.) porous polyethylene matrix (Bolab, Inc.) with an average pore size of 65 μm.) Total tissue pressure (Ptot) was ...
R A, Brace, A C, Guyton
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The evaluation of the soil pressure distribution and carcass stiffness resulting from pneumatic agricultural tyres [PDF]
, 2010 Introducing loads onto the soil via pneumatic tyred equipment is the major cause of compaction of agricultural soils, which causes damage to the soil-water-air-plant system.
Misiewicz, Paula Aleksandra
core