Results 51 to 60 of about 11,847,871 (295)
The Law of the Total Pressure Loss in Supersonic Streamwise Corner Flow
Journal of Physics: Conference SeriesAbstract The total pressure loss is a critical issue in the design of internal flow channels for hypersonic vehicles. In the flow through the streamwise corner region, the adjacent walls induce secondary flows that exacerbate the viscous effects, thereby intensifying the total pressure loss.
Rui Yang, Jiahui Jin, Yuxin Zhao
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Numerical Investigations into Horseshoe Vortices in Draft Tubes of Bulb Turbines
Journal of Fluid Science and Technology, 2008 The series of flows around the piers in draft tubes of bulb turbines were investigated. The flow fields were assumed to be steady incompressible turbulent flows. The primary factor responsible for total pressure loss in draft tubes was investigated based
Kenji SHINGAI +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Separation control with endwall corner jet in a high-speed compressor cascade
Journal of Thermal Science and Technology, 2017 The influences of the endwall corner jet (ECJ) with different locations, yaw angles and jet-to-inflow total pressure ratios on the aerodynamic performance of a high-speed compressor cascade are parametrically investigated by numerical simulation.
Huaping LIU +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Optimization Study of the Dump Diffuser in Gas Turbine to Reduce Pressure Loss
International Journal of Aerospace Engineering, 2018 As a key component-connecting compressor and the entrance of combustion chamber, the diffuser is able to increase the pressure and slow down the airflow in order to promote efficient combustion as well as avoid a large amount of pressure loss.
Fei Xing +4 more
doaj +1 more source
THE INSERTION LOSS OF POROELASTIC PLATE SILENCERS IN A FLOW DUCT [PDF]
, 2008 Idealized silencers consisting of cavity-backed clamped porous elastic plates parallel to the direction of flow can result in low frequency attenuation of noise in the duct.
Aygun, Haydar
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source