Results 211 to 220 of about 16,040,685 (290)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The impact of sleep habits on emotional and behavioral problems, quality of life, caregiver depression, and burnout in children with autism spectrum disorder. [PDF]

Front Psychiatry
Arici Gürbüz A, Cömertoğlu Arslan S, Bozduman Çelebi S, Binokay H, Altun H.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The relationship between parenting stress and preschool children's screen dependence: the chain mediating role of parent-child interaction quality and executive function. [PDF]

Front Psychol
Di H, Liu Y, Li H, Yao H.
europepmc   +1 more source

Is Impaired Sleep Quality a Triggering Factor in Melasma Patients? A Cross-Sectional Study. [PDF]

Indian J Dermatol
Avcı C, Akın G, Akarsu S, İlknur T.
europepmc   +1 more source

Atopic Dermatitis, Sleep Quality, and Cognitive Difficulties in US Adults: A 2024 NHIS Mediation Analysis. [PDF]

Exp Dermatol
Schneiderman M, Del Duca E, Golant A, Guttman-Yassky E, Ungar B.   +4 more
europepmc   +1 more source

EVIDENCE-BASED REVIEW & RECOMMENDATIONS FROM THE BRAZILIAN SOCIETY OF SHOULDER AND ELBOW SURGERY: REVERSE VERSUS ANATOMIC TOTAL ARTHROPLASTY FOR THE TREATMENT OF PRIMARY GLENOHUMERAL OSTEOARTHRITIS WITH AN INTACT ROTATOR CUFF IN PATIENTS AGED 70 YEARS OR OLDER. [PDF]

Acta Ortop Bras
Fernandes MR, Zanesco L, Murachovsky J, Mouraria GG, Lara PHS, Belangero PS, de Medeiros JF, Malavolta EA.   +7 more
europepmc   +1 more source

An observational comparative study of Hass avocado fruit quality and its associations with rhizosphere soil properties across four representative orchards in China. [PDF]

Front Plant Sci
Yang C, Zhao L, Zhang X, Luo C, Wang T, Zhang B, Yang X, Shi Z, Zhao W, Xu J, Sun L.   +10 more
europepmc   +1 more source

Sleep-Timing Types and Weekend Catch-Up Sleep Patterns Associated With Above-Threshold Anxiety Symptoms in College Students: 28-Day Objective Monitoring. [PDF]

Stress Health
Zhou G, Zhang Z, Bu J, Gao S.
europepmc   +1 more source