Results 91 to 100 of about 1,020,351 (295)

Total and Differential Cross Sections for the pp-->pp eta-prime Reaction Near Threshold

, 2003
The eta-prime meson production in the reaction pp-->pp eta-prime has been studied at excess energies of Q = 26.5, 32.5 and 46.6 MeV using the internal beam facility COSY-11 at the cooler synchrotron COSY.
Adam, H. -H., Budzanowski, A., Czyzykiewicz, R., Geck, I., Grzonka, D., Jarczyk, L., Khoukaz, A., Kilian, K., Kowina, P., Lang, N., Lister, T., Moskal, P., Oelert, W., Piskor-Ignatowicz, C., Quentmeier, C., Rozek, T., Santo, R., Schepers, G., Sefzick, T., Sewerin, S., Siemaszko, M., Smyrski, J., Strzalkowski, A., Taschner, A., Winter, P., Wolke, M., Wustner, P., Zipper, W.   +27 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Near-Threshold eta Meson Production in Proton-Proton Collisions

, 1999
The production of eta mesons has been measured in the proton-proton interaction close to the reaction threshold using the COSY-11 internal facility at the cooler synchrotron COSY.
A. Budzanowski, A. Khoukaz, A. Strzałkowski, Albers, Balewski, Brauksiepe, C. Quentmeier, Calén, Calén, Chiavassa, D. Grzonka, Dombrowski, G. Schepers, Green, H. Dombrowski, J. Smyrski, J.T. Balewski, K. Kilian, L. Jarczyk, Lee, M. Jochmann, M. Köhler, M. Wolke, Maier, Morton, P. Kowina, P. Moskal, P. Wüstner, R. Santo, S. Sewerin, T. Lister, T. Sefzick, U. Seddik, W. Oelert   +33 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Determination of Tritium-Helium-3 differential cross-section in the energy range between 0.6 MeV and 3.3 MeV for tritium depth profiling in solids

Nuclear Materials and Energy
The differential cross-section for the 3He+3H nuclear reaction was measured in a thin tritiated PdTi film that was deposited on a Si wafer. The sample was loaded with 3H2 gas at a temperature of 300 °C and at a pressure of 1.8 bar.
S. Markelj, A. Cvetinović, M. Lipoglavšek, M. Kelemen, M. Čekada, P. Pelicon, M. Payet, C. Grisolia   +7 more
doaj   +1 more source

Reaction cross sections for proton scattering from stable and unstable nuclei based on a microscopic approach

, 2007
Microscopic optical model potential results for reaction cross sections of proton elastic scattering are presented. The applications cover the 10-1000 MeV energy range and consider both stable and unstable nuclei. The study is based on in-medium g-matrix
Arellano, H. F., Girod, M.
core   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source