Results 61 to 70 of about 517,075 (314)

Effects of Urbanization on Water Quality and the Macrobenthos Community Structure in the Fenhe River, Shanxi Province, China

Journal of Chemistry, 2020
The relationships between land use types, water and sediment parameters, and macrobenthos community structures in the upper and middle reaches of the Fenhe River and urbanization intensity were studied.
Linfang Wang, Hua Li, Jinhua Dang, Ying Zhao, Yu’en Zhu, Pengming Qiao   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Implications of suspended sediment in the migration of nutrients at the water-sediment interface in retention reservoirs

Scientific Reports
The significance of suspended sediment in the context of nutrient cycling and distribution in reservoirs is rarely reported in the scientific literature.
Maksymilian Cieśla, Renata Gruca-Rokosz
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Elevated water nutrient levels promote co-occurrence of sediment microbiota in white-leg shrimp (Litopenaeus vannamei) culture ponds

Aquaculture Reports
Aquatic microbiota plays crucial roles in biogeochemical processes. However, whether the water nutrients and co-occurrence of sediment microbiota in white-leg shrimp culture ponds increases during culture is unclear.
Liang Wu, Xiaoli Shi, Jian Wang, Xiafei Zheng, Xueqiao Qian, Shouqi Xie, Baojun Shi, Ruiming Xiao, Bo Wang, Yingli Lian, Jiayi Tang   +10 more
doaj   +1 more source

2DV modelling of sediment transport processes over full-scale ripples in regular asymmetric oscillatory flow [PDF]

, 2008
Wave-induced, steep vortex ripples are ubiquitous features in shallow coastal seas and it is therefore important to fully understand and model the sediment transport processes that occur over them.
Guizien, K, Magar, V, Malarkey, J, O'Donoghue, T, van der Werf, JJ   +4 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source