Results 91 to 100 of about 2,326,184 (282)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

β-diversity of the herbaceous layer plant communities in natural forests and its influencing factors in Henan Province

open access: yesGuangxi Zhiwu
Conducting research on β-diversity(beta diversity)and its components, which reflect spatial or temporal variations in species composition among communities, helps to improve the understanding and knowledge of community structure and its maintenance ...
MENG Wei1,2, DU Xiaojun2,3*, JIAO Zhihua4, GAO Xianming2, LIU Longchang1*, WANG Yu1
doaj   +1 more source

Asymptotic development for the CLT in total variation distance

open access: yesBernoulli, 2016
The aim of this paper is to study the asymptotic expansion in total variation in the Central Limit Theorem when the law of the basic random variable is locally lower-bounded by the Lebesgue measure (or equivalently, has an absolutely continuous component): we develop the error in powers of $n^{-1/2}$ and give an explicit formula for the approximating ...
Bally, V, CARAMELLINO, LUCIA
openaire   +6 more sources

Optimal stopping time and halting set for total variation distance

open access: yes, 2015
An aperiodic and irreducible Markov chain on a finite state space converges to its stationary distribution. When convergence to equilibrium is measured by total variation distance, there exists an optimal coupling and a maximal coupling time.
Coquio, Agnes
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Loading or Unloading? This Is the Question! A Multi-Season Study in Professional Football Players

open access: yesSports
This study examined the impact of training load periodization on neuromuscular readiness in elite football players using the Locomotor Efficiency Index (LEI) as a measure of performance optimization.
Mauro Mandorino   +2 more
doaj   +1 more source

Estimating Ising Models in Total Variation Distance

open access: yes
We consider the problem of estimating Ising models over $n$ variables in Total Variation (TV) distance, given $l$ independent samples from the model. While the statistical complexity of the problem is well-understood [DMR20], identifying computationally and statistically efficient algorithms has been challenging.
Daskalakis, Constantinos   +2 more
openaire   +2 more sources

Cutoff phenomenon for the simple exclusion process on the complete graph

open access: yes, 2011
We study the time that the simple exclusion process on the complete graph needs to reach equilibrium in terms of total variation distance.
Lacoin, Hubert, Leblond, Remi
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Female social response to male sexual harassment in poeciliid fish: A comparison of six species

open access: yesFrontiers in Psychology, 2015
Sexual harassment is common among poeciliid fish. In some fishes, males show a high frequency of sneak copulation; such sexual activity is costly to the females in terms of foraging efficiency. In mosquitofish (Gambusia holbrooki), when males are present,
Marco eDadda
doaj   +1 more source

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