Results 111 to 120 of about 45,782 (275)
Totally expanding multiplicative systems [PDF]
A single-matrix multiplicative system consists of an N×N nonnegative matrix Q and an N×1 semi-positive vector x(0). This system is said to be totally expanding if each entry of the sequence {Qnx(0)}n=0,1,… is unbounded.
Rothblum, Uriel G., Denardo, Eric V.
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Accurate computation of the Moore-Penrose inverse of strictly totally positive matrices [PDF]
The computation of the Moore-Penrose inverse of structured strictly totally positive matrices is addressed. Since these matrices are usually very ill-conditioned, standard algorithms fail to provide accurate results.
Marco García, Ana +1 more
core +1 more source
Intraventricular solitary fibrous tumor
Background Solitary fibrous tumor (SFT) is a mesenchymal neoplasm of specialized fibroblastic lineage, which frequently occurs in the subcutaneous and deep soft tissue of pleura,mediastinum, head and neck, extremities and trunk.
Yan-yang CHEN +3 more
doaj
Background Antimicrobial resistance (AMR) is one of the most pressing global public health challenges; in particular, the rapid dissemination of carbapenem-resistant Enterobacterales (CRE) is emerging as a significant concern worldwide. Flies, serving as
Jialiang Xu +11 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Generalized totally nonnegative matrices [PDF]
We define a new class of generalized totally nonnegative matrices, shortly GTN-matrices, over a noncommutative ring with identity and a positive part.
Miroslav Fiedler +3 more
core +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Some extremal problems for strictly totally positive matrices [PDF]
For a strictly totally positive M × N matrix A we show that the ratio ∥Ax∥p∥x∥p has exactly R = min{ M, N} nonzero critical values for each fixed p ϵ (1, ∞). Letting λi denote the ith critical value, and xi an associated critical vector, we show that λ1 >
Pinkus, A.
core +1 more source

