Results 121 to 130 of about 45,782 (275)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Interlacing inequalities for totally nonnegative matrices [PDF]
, 2002 Suppose λ1⩾⋯⩾λn⩾0 are the eigenvalues of an n×n totally nonnegative matrix, and λ̃1⩾⋯⩾λ̃k are the eigenvalues of a k×k principal submatrix. A short proof is given of the interlacing inequalities:λi⩾λ̃i⩾λi+n−k,i=1,…,k.It is shown that if k=1,2,n−2,n−1, λi
Li, Chi-Kwong +4 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Lattice-ordered matrix algebras containing positive cycles [PDF]
, 2013 It is shown that if a lattice-ordered n × n (n ≥ 2) matrix ring over a totally ordered integral domain or division ring containing a positive n-cycle, then it is isomorphic to the lattice-ordered n × n matrix ring with entrywise lattice ...
Ma, Jingjing
core +1 more source
Totally Positive Density Matrices and Linear Preservers [PDF]
, 2016 The intersection between the set of totally nonnegative matrices, which are of interest in many areas of matrix theory and its applications, and the set of density matrices, which provide the mathematical description of quantum states, are investigated ...
Levick, Jeremy +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Subdirect sums of P(P0)-matrices and totally nonnegative matrices [PDF]
, 2008 In this paper, the problem of when the sub-direct sum of two strictly diagonally dominant P-matrices is a strictly diagonally dominant P-matrix is studied. In particular, it is shown that the subdirect sum of overlapping principal submatrices of strictly
Mou, Gu-Fang +4 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
On the characterization of totally nonpositive matrices [PDF]
, 2016 The final publication is available at Springer via http://dx.doi.org/10.1007/s40324-016-0073-1[EN] A nonpositive real matrix $A= (a_{ij})_{1 \leq i, j \leq n}$ is said to be totally nonpositive (negative) if all its minors are nonpositive (negative) and ...
Pelaez, María J. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source