Results 61 to 70 of about 481,513 (273)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2015 exterior viewHandwritten on reverse: The grey Creole and pink Etowah marble are from the Tate quarries of Georgia. The coquina rock was excavated at Daytona and is similar to that first used by the Spaniards in building the fort at St. Augustine.
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
FE Simulation of Transmission Tower
Advances in Civil Engineering, 2014 The vital components of the transmission line are the electrical transmission towers. They are commonly used to support the phase conductors and shield wires of a transmission line.
Boshra Eltaly, Amen Saka, Kamel Kandil
doaj +1 more source
The Binary Cooling Tower Process: An Energy Conserving Water Reuse Technology
, 1981 The Binary Cooling Tower (BCT) harnesses cooling system waste heat to accomplish concentration of waste and process streams. The BCT can also be integrated to isolate and improve the efficiency of critical cooling loops. This paper describes the BCT, its
Sanderson, W. G. +2 more
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, 2013 This paper describes the modeling of a high-temperature storage system for an existing solar tower power plant with open volumetric receiver technology, which uses air as heat transfer medium (HTF).
Alexopoulos, Spiros +6 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Remote Airport Tower Operation with Augmented Vision Video Panorama HMI
, 2006 In this paper the initial results of the DLR project Remote Airport Tower Operation Research (RapTOr) are described. Within this project an augmented vision video panorama system and a corresponding HMI is developed for remote surface movement management
Schmidt, Markus +3 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source