Results 161 to 170 of about 11,471 (211)
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Lancet, The, 1998
1coined the term necrolysis to describe four clinical cases characterised pathologically by necrosis of the epidermis, and clinically by widespread epidermolysis—a loosening of the epidermis leading to blister formation, exfoliation, or both. Large sheets of skin had peeled off, leaving a raw, denuded base.
exaly +3 more sources
1coined the term necrolysis to describe four clinical cases characterised pathologically by necrosis of the epidermis, and clinically by widespread epidermolysis—a loosening of the epidermis leading to blister formation, exfoliation, or both. Large sheets of skin had peeled off, leaving a raw, denuded base.
exaly +3 more sources
International Journal of Dermatology, 1991
Toxic Epidermal Necrolysis (TEN) is an acute, severe, often life-threatening skin reaction, which is characterized by an extensive necrosis and detachment of the epidermis and mucous membranes. It has been observed worldwide and affects people of both sexes and all ages.
T E, Rohrer, A R, Ahmed
+10 more sources
Toxic Epidermal Necrolysis (TEN) is an acute, severe, often life-threatening skin reaction, which is characterized by an extensive necrosis and detachment of the epidermis and mucous membranes. It has been observed worldwide and affects people of both sexes and all ages.
T E, Rohrer, A R, Ahmed
+10 more sources
Current Drug Safety, 2012
Toxic epidermal necrolysis (TEN) is a severe mucocutaneous drug-induced syndrome that causes massive keratinocyte apoptosis and therefore hydro-electrolytic disorders and systemic infection. TEN approximately affects one to two cases per million per year. Mortality rate may reach thirty percent of cases. Thus, TEN constitute a therapeutic emergency at
Florence, Castelain, Philippe, Humbert
openaire +3 more sources
Toxic epidermal necrolysis (TEN) is a severe mucocutaneous drug-induced syndrome that causes massive keratinocyte apoptosis and therefore hydro-electrolytic disorders and systemic infection. TEN approximately affects one to two cases per million per year. Mortality rate may reach thirty percent of cases. Thus, TEN constitute a therapeutic emergency at
Florence, Castelain, Philippe, Humbert
openaire +3 more sources
International Journal of Dermatology, 1996
Abstract Background. Most studies on drug‐induced toxic epidermal necrolysis (TEN) report a high mortality rate. This has been attributed partly to the use of corticosteroids for its treatment. However, we consider corticosteroids to be the sheet anchor for saving the patients having TEN. Materials and Methods.
J S, Pasricha +4 more
openaire +4 more sources
Abstract Background. Most studies on drug‐induced toxic epidermal necrolysis (TEN) report a high mortality rate. This has been attributed partly to the use of corticosteroids for its treatment. However, we consider corticosteroids to be the sheet anchor for saving the patients having TEN. Materials and Methods.
J S, Pasricha +4 more
openaire +4 more sources
Postgraduate Medicine, 1972
Toxic epidermal necrolysis, although uncommon, warrants the attention of all clinicians because of its serious prognosis. The clinical course of this cutaneous syndrome is similar in children and adults, but some differences do exist. Because diagnostic laboratory tests are not available, the physician must recognize the disorder by its distinctive ...
A J, Ammann, W H, Tooley, R, Hong
+7 more sources
Toxic epidermal necrolysis, although uncommon, warrants the attention of all clinicians because of its serious prognosis. The clinical course of this cutaneous syndrome is similar in children and adults, but some differences do exist. Because diagnostic laboratory tests are not available, the physician must recognize the disorder by its distinctive ...
A J, Ammann, W H, Tooley, R, Hong
+7 more sources
Journal of Burn Care & Rehabilitation, 1997
Toxic epidermal necrolysis (TEN) is a poorly understood and devastating condition. It is usually diagnosed in a primary care setting. Treatment of severe cases by burn care personnel is usually by referral. In this review, we report excessive mortality rates associated with prolonged use of systemic steroid therapy and delayed referral (more than 1 ...
J T, Murphy, G F, Purdue, J L, Hunt
openaire +2 more sources
Toxic epidermal necrolysis (TEN) is a poorly understood and devastating condition. It is usually diagnosed in a primary care setting. Treatment of severe cases by burn care personnel is usually by referral. In this review, we report excessive mortality rates associated with prolonged use of systemic steroid therapy and delayed referral (more than 1 ...
J T, Murphy, G F, Purdue, J L, Hunt
openaire +2 more sources
Southern Medical Journal, 1964
A DIFFUSE bullous eruption of acute onset associated with marked skin tenderness was described in 1956 by Lyell1 as well as Lang and Walker.2 Subsequently, Beare3 reviewed the literature and described. the clinical and histologic manifestations of 10 cases observed in Irish adults and children.
I M, FREEDBERG, R B, BERG
openaire +4 more sources
A DIFFUSE bullous eruption of acute onset associated with marked skin tenderness was described in 1956 by Lyell1 as well as Lang and Walker.2 Subsequently, Beare3 reviewed the literature and described. the clinical and histologic manifestations of 10 cases observed in Irish adults and children.
I M, FREEDBERG, R B, BERG
openaire +4 more sources