Results 181 to 190 of about 17,217 (221)
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Archives of Dermatology, 1960
A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1or epidermolysis necroticans combustiformis by Soltermann.2Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3However, no recent ...
B, POTTER, R, AUERBACH, A L, LORINCZ
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A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1or epidermolysis necroticans combustiformis by Soltermann.2Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3However, no recent ...
B, POTTER, R, AUERBACH, A L, LORINCZ
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Advances in toxic epidermal necrolysis
Seminars in Cutaneous Medicine and Surgery, 1996On the basis of the clinicopathologic and causative characteristics, one can separate an erythema multiformis spectrum from a toxic epidermal necrolysis (TEN)-Stevens Johnson syndrome which is a drug induced disease. Despite a well-known clinical aspect, several cutaneous diseases may be mistaken for TEN.
J E, Revuz, J C, Roujeau
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Interventions for toxic epidermal necrolysis
Cochrane Database of Systematic Reviews, 2002Toxic epidermal necrolysis is a rare condition where a drug reaction induces skin loss, similar to that seen in extensive burns. It is associated with high morbidity and mortality and there is no clear agreement on effective treatment.To assess the effects of all interventions for the treatment of toxic epidermal necrolysis.We searched the Cochrane ...
S, Majumdar +3 more
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International Journal of Dermatology, 1992
Toxic epidermal necrolysis is a severe mucocutaneous reaction pattern characterized by fever, systemic toxicity, tenderness, erythema, and widespread exfoliation. Lyell1 of Glasgow, Scotland, and Lang and Walker2 of Cape Town, South Africa, independently described this syndrome in 1956.
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Toxic epidermal necrolysis is a severe mucocutaneous reaction pattern characterized by fever, systemic toxicity, tenderness, erythema, and widespread exfoliation. Lyell1 of Glasgow, Scotland, and Lang and Walker2 of Cape Town, South Africa, independently described this syndrome in 1956.
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Plastic and Reconstructive Surgery, 1978
We present a case report of a patient with toxic epidermal necrolysis (TEN), associated with therapy with trimethoprin and sulfamethoxazole. Because of the similarity of TEN to an extensive partial-thickness burn, and the favorable response to the treatment used in burns, surgeons who treat burns should be familiar withe disease and take an active role
G, Anhalt, C F, Snelling
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We present a case report of a patient with toxic epidermal necrolysis (TEN), associated with therapy with trimethoprin and sulfamethoxazole. Because of the similarity of TEN to an extensive partial-thickness burn, and the favorable response to the treatment used in burns, surgeons who treat burns should be familiar withe disease and take an active role
G, Anhalt, C F, Snelling
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Plasmapheresis in toxic epidermal necrolysis
International Journal of Dermatology, 1997Abstract Background The treatment of toxic epidermal necrolysis (TEN) is usually based on the removal of the offending drug(s), fluid replacement, nutritional support, and local management. The mortality and morbidity, however, remain high and the death rate may be reduced to 10% only in special centers that use biologic dressings. Plasma exchange (PE)
G C, Chaidemenos +5 more
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Current Opinion in Allergy & Clinical Immunology, 2013
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions.
Haur-Yueh, Lee, Wen-Hung, Chung
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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions.
Haur-Yueh, Lee, Wen-Hung, Chung
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Pharmacogenetics of toxic epidermal necrolysis
Expert Opinion on Pharmacotherapy, 2010Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are two of the most severe drug-induced cutaneous reactions. Advances in genome technologies have allowed researchers to identify genetic markers associated with this drug-associated event and these have provided a potential tool for prevention.Current updates of genetic biomarkers ...
Ming Ta Michael, Lee +3 more
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Intestinal toxic epidermal necrolysis
Gazzetta Medica Italiana Archivio per le Scienze Mediche, 2018Toxic epidermal necrolysis (TEN), also known as the Stevens-Johnson Syndrome (SJS), is defined as severe, lifethreatening mucocutaneous reactions, predominantly drug induced, but also associated with infectious diseases. Clinical manifestations consist of erythematous cutaneous lesions, with blister formation and epidermal detachment as a consequence ...
Cudia, Antonella +4 more
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Management of toxic epidermal necrolysis
Hospital Medicine, 2000Toxic epidermal necrolysis and Stevens–Johnson syndrome are rare, life-threatening drug reactions. Widespread epidermal necrosis and mucosal erosions lead to complications similar to those developing after extensive burns. Treatment is supportive. The role of steroids and other potential disease-modifying agents remains to be established by controlled ...
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