Results 11 to 20 of about 29,800 (242)

Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management

Medicina, 2021
Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin.
R. Frantz, Simo Huang, Abhi C. Are, K. Motaparthi   +3 more
semanticscholar   +1 more source

Stevens-Johnson syndrome and toxic epidermal necrolysis: A systematic review of PubMed/MEDLINE case reports from 1980 to 2020

Frontiers in Medicine, 2022
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life-threatening immunologic reactions. Prior studies using electronic health records, registries or reporting databases are often limited in sample size or lack ...
Liqin Wang, Sheril Varghese, F. Bassir, Ying-Chin Lo, Carlos A. Ortega, Sonam N. Shah, K. Blumenthal, E. Phillips, Li Zhou   +8 more
semanticscholar   +1 more source

A Review of the Systemic Treatment of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

Biomedicines, 2022
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are uncommon but life-threatening diseases mostly caused by drugs. Although various systemic immunomodulating agents have been used, their therapeutic efficacy has been inconsistent ...
Hua-Ching Chang, T. Wang, Ming-Hsiu Lin, Ting-Jui Chen   +3 more
semanticscholar   +1 more source

Bullous pemphigoid mimicking toxic epidermal necrolysis [PDF]

Anais Brasileiros de Dermatologia
Hiram Larangeira de Almeida Jr., Rodrigo Piltcher da Silva, Valéria Magalhães Jorge   +2 more
doaj   +2 more sources

Scoring Assessments in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Frontiers in Medicine, 2022
Epidermal necrolysis, the unifying term for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), is a severe cutaneous drug reaction associated with high morbidity and mortality.
A. Dobry, S. Himed, Margo Waters, B. Kaffenberger   +3 more
semanticscholar   +1 more source

Toxic Epidermal Necrolysis [PDF]

BMJ, 1961
Summary Six cases of toxic epidermal necrolysis occurringin small children are described. The condition, as it presents in children, is described and discussed.
Eilish Ridge, S. G. Browne
openaire   +5 more sources

Combination of cyclosporine A and methylprednisolone to treat pediatric Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome

Dermatology Reports, 2023
The treatment of epidermal necrolysis in pediatric patients remains a major challenge. Cyclosporine A has emerged as a promising therapy for epidermal necrolysis in adults; however, its efficacy in children is unclear.
Shinta Trilaksmi Dewi, Laily Noor Qomariah, Widya Khairunisa Sarkowi, Monika Puspitasari, Miya Khalidah, Marcella Anggatama, Dwinanda Almira Rizkiani, Kristiana Etnawati, Sri Awalia Febriana   +8 more
doaj   +1 more source

Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis

Science Translational Medicine, 2021
Neutrophil extracellular traps induced by drug-specific CD8+ T cells initiate SJS/TEN. Skin-deep drug reactions Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are similar life-threatening forms of severe cutaneous adverse drug ...
M. Kinoshita, Y. Ogawa, N. Hama, I. Ujiie, A. Hasegawa, Saeko Nakajima, T. Nomura, J. Adachi, Takuya Sato, S. Koizumi, S. Shimada, Y. Fujita, Hayato Takahashi, Y. Mizukawa, T. Tomonaga, K. Nagao, R. Abe, T. Kawamura   +17 more
semanticscholar   +1 more source

Case Report: Enfortumab Vedotin for Metastatic Urothelial Carcinoma: A Case Series on the Clinical and Histopathologic Spectrum of Adverse Cutaneous Reactions From Fatal Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis to Dermal Hypersensitivity Reaction

Frontiers in Oncology, 2021
Enfortumab vedotin is a Nectin-4 directed antibody-drug conjugate approved in metastatic urothelial carcinoma following progression on a platinum-containing chemotherapy and immune checkpoint blockade.
Paul V Viscuse, Mario L. Marques-Piubelli, M. Heberton, E. Parra, A. Shah, A. Siefker-Radtke, Jianjun Gao, S. Goswami, D. Ivan, J. Curry, M. Campbell   +10 more
semanticscholar   +1 more source

Supportive care in the acute phase of Stevens–Johnson syndrome and toxic epidermal necrolysis: an international, multidisciplinary Delphi‐based consensus

British Journal of Dermatology, 2021
Supportive care is the cornerstone of management of adult and paediatric Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, consensus on the modalities of supportive care is lacking.
M. Brüggen, S. Le, S. Walsh, A. Toussi, N. Prost, A. Ranki, B. Didona, A. Colin, B. Horváth, E. Brezinová, B. Milpied, C. Moss, C. Bodemer, D. Meyersburg, C. Sălăvăstru, G. Tiplica, E. Howard, É. Béquignon, J. Bouwes Bavinck, J. Newman, J. Gueudry, M. Nägeli, K. Zaghbib, K. Pallesen, A. Bygum, P. Joly, P. Wolkenstein, S. Chua, R. Le floch, N. Shear, C. Chu, N. Hama, R. Abe, W. Chung, T. Shiohara, M. Ardern-Jones, P. Romanelli, E. Phillips, R. Stern, J. Cotliar, R. Micheletti, A. Brassard, J. Schulz, R. Dodiuk-Gad, A. Dominguez, A. Paller, L. Seminario-Vidal, A. Mostaghimi, M. Noe, S. Worswick, D. Tartar, R. Sheridan, B. Kaffenberger, K. Shinkai, E. Maverakis, L. French, S. Ingen-Housz-Oro   +56 more
semanticscholar   +1 more source