Results 11 to 20 of about 13,087 (176)
Toxic epidermal necrolysis [PDF]
F1000Research, 2016 Toxic epidermal necrolysis (TEN) is a rare, life-threatening drug-induced skin disease with a mortality rate of approximately 30%. The clinical hallmark of TEN is a marked skin detachment caused by extensive keratinocyte cell death associated with mucosal involvement. The exact pathogenic mechanism of TEN is still uncertain.
Hoetzenecker, Wolfram +7 more
openaire +3 more sources
Pembrolizumab-Induced Toxic Epidermal Necrolysis
Case Reports in Oncology, 2022 Immunotherapy has nowadays become part of the mainstay of treatment for several cancers. In this report, we present a case of toxic epidermal necrolysis (TEN) occurring as a relatively rare complication of pembrolizumab, which is a humanized monoclonal ...
Luca Borg +5 more
doaj +1 more source
Identifying the incidence of rash, Stevens-Johnson syndrome and toxic epidermal necrolysis in patients taking lamotrigine: a systematic review of 122 randomized controlled trials [PDF]
Anais Brasileiros de Dermatologia, 2017 Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic
Romi Bloom, Kyle T. Amber
doaj +2 more sources
Fulvestrant-induced toxic epidermal necrolysis [PDF]
Anais Brasileiros de Dermatologia, 2019 Toxic epidermal necrolysis is a condition with massive keratinocyte apoptosis, and it is associated with high mortality rates. Fulvestrant, an estrogen receptor antagonist, is indicated in the treatment of estrogen receptor-positive metastatic breast ...
Macarena Morales-Conde +3 more
doaj +1 more source
Burns Open, 2017 Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový +8 more
doaj +1 more source
The Journal of Emergency Medicine, 1989 Toxic epidermal necrolysis (TEN) is a life-threatening condition in which the epidermis blisters and peels in large sheets. The clinical syndrome and diagnosis are reviewed. Current treatment and prevention of complications are discussed. The key to low morbidity and mortality in TEN is early intervention.
Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA ( host institution ) +4 more
openaire +5 more sources
Ceftriaxone-induced toxic epidermal necrolysis mimicking burn injury: a case report
Journal of Medical Case Reports, 2009 Introduction Toxic epidermal necrolysis is a rare exfoliative disorder with a high mortality rate. Case presentation We present a 70-year-old woman of Iranian descent who presented with toxic epidermal necrolysis that was initially diagnosed as a scald ...
Billig Allan, Cohen Sarit, Ad-El Dean
doaj +1 more source
Case Reports in Dermatological Medicine, 2020 Toxic epidermal necrolysis is a life-threatening dermatological emergency with high mortality if not treated in time. Here we report a case of toxic epidermal necrolysis due to carbamazepine in rural Nepal in COVID-19 pandemic who was successfully ...
Vikash Paudel, Deepa Chudal
doaj +1 more source
Toxic epidermal necrolysis induced by lamotrigine treatment in a child [PDF]
Korean Journal of Pediatrics, 2014 Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis.
Youngsuk Yi, Jeong Ho Lee, Eun Sook Suh
doaj +1 more source
Toxic epidermal necrosis associated with afatinib: A case report and literature review
Frontiers in Oncology, 2023 ObjectiveTo report a case of afatinib-induced toxic epidermal necrosis (TEN), in a patient with metastatic non-small cell lung cancer (NSCLC) and compare these findings with that of evaluate similarities and differences to other cases reported in the ...
Wei Yang, Yansong Lu, Ze Wu, Jun Niu
doaj +1 more source