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Toxic Epidermal Necrolysis: Reply [PDF]

Medical Journal Armed Forces India, 2007
Dear Editor, The authors wish to thank the reader for the keen interest shown in the article and for his compliments. We would like to clarify the issues raised by him. Toxic Epidermal Necrolysis (TEN) has been reported to develop due to corticosteroids as well as in spite of steroid therapy [1].
N, Kumar, N S, Walia
openaire   +2 more sources

Toxic Epidermal Necrolysis

Journal of Rawalpindi Medical College, 2020
Toxic epidermal necrolysis (TEN) is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and
Syed Naveed Ali Shah, Ifaza Tariq, Muhammad Nauman Zafar   +2 more
doaj  

Carbamazepine-Induced Toxic Epidermal Necrolysis

Journal of Integrated Health Sciences, 2018
Toxic epidermal necrolysis (TEN) is an uncommon; however, life-threatening dermatological condition which occurs most frequently by the use of drugs. Some group of medications, such as antiepileptics, antibiotics as well as antivirals, can induce such ...
Kushal Gohel, Rashmi Mahajan, Megha Patel, Harsh Patel   +3 more
doaj   +1 more source

HLA‐B*15:21 carrier status is a susceptibility factor of carbamazepine‐induced nonimmediate cutaneous adverse reactions in HLA‐B*15:02‐negative patients: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon, Chutima Seree‐aphinan, Antida Sangiemchoey, Khwanchanok Kaewpiboon, Taweesak Maneerot, Oradawan Plong‐on, Pornsiri Sangmanee, Punthipa Nichanon, Jariya Khayman, Jiraphan Manee, Areerat Hnoonual, Kanoot Jaruthamsophon   +11 more
wiley   +1 more source

Toxic Epidermal Necrolysis

Eurasian Journal of Medicine, 2019
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Gülten Gürel, Ökkeş Sipahi, Faik Gençer   +2 more
doaj   +2 more sources

A case series of allopurinol-induced toxic epidermal necrolysis

Indian Journal of Dermatology, 2011
This is a case series of allopurinol-induced toxic epidermal necrolysis. Revisiting the indications of using allopurinol in asymptomatic hyperuricemia and a critical reappraisal of the safety profile of allopurinol is done in this article.
Harneet Ranu, Jackson Jiang, Pang Shiu Ming   +2 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

Clinical Pharmacology &Therapeutics, EarlyView.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow, Brendan Day, Esther H. Zhou, Corinne Woods, Nana Dwumfour, Jenni Y. Lee, Ilynn Bulatao, Sanae Cherkaoui, Manish Kalaria, Sonja Brajovic, Nabila Sadiq, Farideh Sistani, Maggie Lee, Grace Chai, Gerald Dal Pan   +14 more
wiley   +1 more source

Toxic epidermal necrolysis following a furosemide injection: a case report

Journal of Medical Case Reports
Background Toxic epidermal necrolysis is a life threatening adverse cutaneous reaction mostly following drug administration. It is characterized by extensive detachment of skin and mucous membranes with a more than 30% total body surface area involvement.
Clare Nakubulwa, Deogratius Galagala, Ivan Gidudu   +2 more
doaj   +1 more source

Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale

Clinical Case Reports, 2022
Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile.
Bishal Dhakal, Sagun Dawadi, Laxman Khadka, Sujan Bohara, Shashank Neupane, Priajan Ale Magar, Bishnu Deep Pathak, Binit Upadhaya Regmi   +7 more
doaj   +1 more source