Results 31 to 40 of about 17,156 (210)

Clinical features of Stevens — Johnson syndrome and toxic epidermal necrolysis: An observational cohort retrospective study

Кубанский научный медицинский вестник
Background. Stevens — Johnson syndrome and toxic epidermal necrolysis are severe diseases featuring lesions of the mucous membranes and skin, with a possible lethal outcome. These diseases are most often triggered by various infections and medications, e.
G. M. Nurtdinova, E. S. Galimova, O. I. Kucher, D. D. Gazizova, A. F. Galyautdinov, Z. R. Khismatullina, N. Sh. Zagidullin   +6 more
doaj   +1 more source

Acute compartment syndrome of the forearm as a rare complication of toxic epidermal necrolysis: a case report

Journal of Medical Case Reports, 2012
Introduction Toxic epidermal necrolysis lies within the spectrum of severe cutaneous adverse reactions induced by drugs, affecting skin and mucous membranes.
Kamal Tamer, Elnikety Sherif, Mashaly Heba, Casha James   +3 more
doaj   +1 more source

Early Bilateral Amniotic Membrane Transplantation in the Management of Severe Ocular Involvement from Acute Toxic Epidermal Necrolysis in a Chinese Pediatric Patient [PDF]

, 2014
Introduction: Toxic Epidermal Necrolysis (TEN) is a rare but potentially life-threatening muco-cutaneous condition associated with idiosyncratic hypersensitivity to certain drugs.
Chan, CYJ, Chan, KSK, Lai, JSM, Shih, KC, Yim, SM, Yuen, LH   +5 more
core   +1 more source

Carbamazepine-Induced Toxic Epidermal Necrolysis

Journal of Integrated Health Sciences, 2018
Toxic epidermal necrolysis (TEN) is an uncommon; however, life-threatening dermatological condition which occurs most frequently by the use of drugs. Some group of medications, such as antiepileptics, antibiotics as well as antivirals, can induce such ...
Kushal Gohel, Rashmi Mahajan, Megha Patel, Harsh Patel   +3 more
doaj   +1 more source

Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications [PDF]

, 2014
Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes.
Basu, Sayan, Gomes, José Álvaro Pereira, Joo, Choun-Ki, Kannabiran, Chitra, Kim, Mee Kum, Kinoshita, Shigeru, Lee, Hyo Seok, Rathi, Varsha, Sangwan, Virender, Seo, Kyoung Yul, Shamaila, Almas, Sotozono, Chie, Tokunaga, Katsushi, Ueta, Mayumi, Wakamatsu, Tais Hitomi, Yoon, Kyung-Chul, Yoon, Sangchul   +16 more
core   +2 more sources

A case series of allopurinol-induced toxic epidermal necrolysis

Indian Journal of Dermatology, 2011
This is a case series of allopurinol-induced toxic epidermal necrolysis. Revisiting the indications of using allopurinol in asymptomatic hyperuricemia and a critical reappraisal of the safety profile of allopurinol is done in this article.
Harneet Ranu, Jackson Jiang, Pang Shiu Ming   +2 more
doaj   +1 more source

Rapid recovery of postnivolumab vemurafenib-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome after tocilizumab and infliximab administration [PDF]

, 2020
Background Immune checkpoint inhibitors such as nivolumab and targeted BRAF inhibitors have dramatically altered the treatment outcomes of metastatic melanoma over the past few years. Skin toxicity is the most common adverse event (AE) related to the
Maestro, Alessandra, Marcuzzi, Annalisa, Maximova, Natalia, Zanon, Davide   +3 more
core   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

Toxic Epidermal Necrolysis

Eurasian Journal of Medicine, 2019
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Gülten Gürel, Ökkeş Sipahi, Faik Gençer   +2 more
doaj   +2 more sources

Ciprofloxacin induced toxic epidermal necrolysis with cholestatic hepatitis: A case report with literature review and revisit to the Naranjo adverse drug reaction probability scale

Clinical Case Reports, 2022
Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile.
Bishal Dhakal, Sagun Dawadi, Laxman Khadka, Sujan Bohara, Shashank Neupane, Priajan Ale Magar, Bishnu Deep Pathak, Binit Upadhaya Regmi   +7 more
doaj   +1 more source