Results 51 to 60 of about 17,156 (210)

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Important Points in Toxic Epidermal Necrolysis Management

Oman Medical Journal, 2019
There are several important points that the authors did not highlight which are critical and form the cornerstones in the care of patients with possible TEN.
Sultan
doaj   +1 more source

Epidermal necrolysis: SCORTEN performance in AIDS and non-AIDS patients [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela.
Carlos Gustavo Wambier, Thaís Angélica Hoekstra, Sarah Perillo de Farias Wambier, Roberto Bueno Filho, Fernando Crivelenti Vilar, Renato Soriani Paschoal, Ana Maria Roselino, Marco Andrey Cipriani Frade, Norma Tiraboschi Foss   +8 more
doaj   +1 more source

Striking enhancement at the site of radiation for nivolumab-induced Stevens-Johnson syndrome [PDF]

, 2018
Stevens-Johnson syndrome is a rare adverse cutaneous drug reaction characterized by epidermal detachment of
Al-Omari, Ahmed, Rancour, Elizabeth A., Shah, Kishan M.   +2 more
core  

Efficacy and Tolerability of Weekly Bortezomib, Lenalidomide, and Dexamethasone Protocols in Transplant‐Ineligible Newly Diagnosed Myeloma: An Australian Real‐World, Multicenter Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
RVD with weekly bortezomib dosing in real‐world newly diagnosed transplant‐ineligible myeloma shows comparable efficacy and reduced toxicity compared to twice‐weekly trial protocols. ABSTRACT Background Lenalidomide, bortezomib, and dexamethasone (RVD) remains a standard of care regimen for newly diagnosed multiple myeloma in centers without access to ...
Samantha Kurniawan, Angela Hwang, Nicole Wong Doo, Tracy King, Christian Bryant, Jennifer Zhang, Kristina Whelan, Parisa Fani‐Molky, Giselle Kidson‐Gerber, Annmarie Bosco, Nada Hamad, Gurdeep Parmar, Fiona Kwok, Sam Lai, Silvia Ling, P. Joy Ho, Georgia McCaughan, Adam Bryant   +17 more
wiley   +1 more source

Toxic epidermal necrolysis in a 5-year-old boy - case report

Brazilian Dental Science, 2016
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered a spectrum of acute life-threatening mucocutaneous reaction that differ only in severity, often induced by drugs.
Pavan Puri, Sana Shaikh, Adesh Kakade, Rajiv Desai, Rahul Rahinj, Pankaj Shirsat   +5 more
doaj   +1 more source

Cutaneous approach in toxic epidermal necrolysis [PDF]

Revista Brasileira de Cirurgia Plástica, 2017
INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto, Pedro Salomão Piccinini, Jean Miguel Andary, Lucas Dal Pozzo Sartori, Lucas Tomkowski Cancian, Carlos Oscar Uebel, Milton Paulo de Oliveira   +6 more
doaj   +1 more source

SCORTEN and Novel Prognostic Markers in Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis: A Systematic Review and Meta‐Analysis

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe skin reaction with high mortality, most often triggered by medications. Early identification of patients at risk is essential for guiding treatment. The SCORTEN score, comprising seven clinical and laboratory variables, is widely used to predict mortality but may ...
Zhao Feng Liu, Howard Yang, Lawrence Lin, Ash Tyagi, Amy Sylivris, Adithya Shastry, Nidhin Sunil Kuruvilla, Douglas Gin, Christopher Y. Chew   +8 more
wiley   +1 more source

Cephazolin-Induced Toxic Epidermal Necrolysis Treated with Intravenous Immunoglobulin and N-Acetylcysteine

Case Reports in Immunology, 2012
Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and ...
Carlos Saavedra, Paola Cárdenas, Héctor Castellanos, Kateir Contreras, J. R. Castro   +4 more
doaj   +1 more source

Toxic Epidermal Necrolysis in an Irradiated Patient Treated with a Nanocrystalline Silver Dressing

Case Reports in Dermatology, 2012
Toxic epidermal necrolysis syndrome is a severe exfoliative condition, which may be triggered by anticonvulsant medication. We report a case of toxic epidermal necrolysis syndrome in a 43-year-old female who was receiving radiotherapy for brain ...
Tamara Z. Vern-Gross, Areta Kowal-Vern, Stathis J. Poulakidas   +2 more
doaj   +1 more source